Fortunately, more and more CBD research is being done these days, especially now that cannabis has become legal in more and more places. In this article we list 9 conditions in which – according to scientific studies – CBD oil can positively influence your health!
Oil by far the most popular form of CBD consumption
Cannabidiol – or CBD – is a chemical compound found in the cannabis plant. When applied topically or consumed by inhalation, sublingually (drip under the tongue), or through edibles, CBD interacts with the neuroreceptors in your endocannabinoid system. That’s responsible for the signals between your cells to help regulate your movement, mood, homeostasis and immune system.
CBD is extracted from the cannabis plant and mixed with an inert before consumption carrier oil such as hemp seed oil. Of the roughly 60% of U.S. adults who report having used CBD before, 55% use CBD oil or a tincture, according to one recent Forbes Health survey among 2,000 people.
1. Reduction of Anxiety and Depression
CBD’s ability to calm down is perhaps its most popular effect and why its use is so widespread. A study from 2017 in the Brazilian Journal of Psychiatry tests the anxiety levels of 57 men in a simulated fluency test.
Some are given a placebo, while others are given 150 milligrams, 300 mg or 600 mg of CBD before giving their speech. Those given 300 milligrams of CBD experienced significantly less anxiety during the test, compared to those given a placebo. Interestingly, participants given 150 or 600 milligrams of CBD experienced more anxiety during the test than the 300 milligram group.
Meanwhile, at least reveals an investigation (on mice) that CBD has effects comparable to the antidepressant imipramine† However, human trials are needed to confirm whether CBD can trigger the same antidepressant response in our bodies.
2. The treatment of certain epilepsy syndromes
In some cases, CBD can be used to treat seizures.
In 2018 approves The Food and Drug Administration (FDA) in the US the use of CBD under the brand name Epidiolex good for the treatment of seizures due to Lennox-Gastaut syndrome and Dravet syndrome (two rare forms of epilepsy) in patients at least 2 years old.
Three well-researched studies form the basis for the FDA’s decision. In these studies, 516 patients with Lennox-Gastaut syndrome or Dravet syndrome will receive Epidiolex or a placebo. Epidiolex, when taken with other prescription medications, reduces the frequency of participants’ seizures compared to the placebo.
3. Reduction of PTSD Symptoms
In a small study from 2018 in The Journal of Alternative and Complementary Medicine Eleven people with post-traumatic stress disorder (PTSD) received CBD — along with routine psychiatric care — for eight weeks. They stay in an outpatient clinic for psychiatric patients. Ten out of eleven experienced a decrease in their PTSD symptoms. CBD is generally well tolerated, the researchers write.
Margaret Rajnic, a nurse practitioner with experience with medicinal cannabis and CBD, emphasizes the importance of using therapy in conjunction with any type of cannabis or CBD for PTSD. “It takes a fair amount of therapy for PTSD,” she says, “but CBD gives you that little bit less anxiety.”
Four other tests on humans from 2012 to 2016 suggest that CBD does indeed reduce PTSD symptoms – some of the substances tested also contain THC, the main mind-altering element in cannabis. When THC and CBD work together, they create a so-called ‘entourage effect’, which complement each other’s benefits and potency. For example, if you take the same dose of THC and CBD together, the “high” of THC is tempered, while a little bit of THC combined with more CBD amplifies the effects of CBD.
4. Treatment of an opioid/opiate addiction
Some research—both preclinical animal and human clinical trials—suggest that CBD could be used to help people kick their opioid addiction, a common problem due to the rampant use of analgesic (often morphine/heroin-based) medications.
In one such research researchers are administering CBD to people with heroin addiction. Over the course of a week, CBD reduced the cravings of the heroin users. Withdrawal anxiety decreases, it lowers the resting heart rate and salivary cortisol levels drop significantly. No serious side effects are found.
Other studies conclude that CBD is helpful in reducing various psychiatric and medical symptoms such as anxiety, insomnia and pain in patients with drug dependence. This indicates that CBD may be an effective treatment for opioid addiction. Further studies are of course still needed.
5. Relief of ALS Symptoms
Amyotrofische laterale sclerose (ALS) is a disease that causes nerve cells in the brain and spinal cord to deteriorate. That results in a loss of muscle control, which gets worse over time. It is not yet clear exactly why ALS occurs, although in some cases it can be hereditary. There is no known cure, and there are only two (FDA-approved) drugs to help treat ALS symptoms.
Research suggests that people with ALS may benefit from the entourage effect created by the combination of THC and CBD. This is similar in effect to people with PTSD. In a research from 2019, patients will be given a combination of THC and CBD in different dosages, depending on their needs and preferences. Those with mild spasticity (muscle tightness and stiffness) due to ALS report a high degree of satisfaction with the treatment. The patients with moderate to severe spasticity report higher satisfaction rates than those with mild spasticity.
6. Relieving untreatable pain
In 2005 Canada approves use of Sativex, an oromucosal (incorporated into the oral mucosa) spray with equal amounts of THC and CBD. It is used as a treatment for multiple sclerosis-related central neuropathic pain. In 2007, Canada reapproved the drug’s use for cancer pain that doesn’t respond to other drugs.
Meanwhile, ongoing studies in the US indicate that CBD is effective in treating chronic, non-cancer-related pain. During the day an investigation from 2020, researchers are administering CBD topically to a group of patients with symptomatic peripheral neuropathy (a result of damage to the cranial nerve and spinal cord), while another group with the same condition is given a placebo. The results show a significant reduction in intense, sharp pains and cold, itchy sensations in those taking CBD, compared to those taking a placebo. None of the participants reported adverse side effects.
When CBD oil is introduced topically it does not affect the major systemic problem as it would if it were administered directly into the bloodstream. Instead, topically applied CBD is more effective at treating pain in a particular area. Because it is applied more directly, it can have a more pronounced effect.
7. CBD Reduces Diabetic Complications
Out tests on human cells, CBD has been shown to help reduce the effects of high glucose levels on other cells in the body, which usually precedes the development of diabetes and various complications. Researchers conclude that with further studies, CBD could have significant benefits when used in patients with diabetes, diabetic complications and the build-up of plaque in the artery walls.
in another small research Thirteen patients with type 2 diabetes who are not receiving insulin treatment will receive both CBD and a placebo (instead of insulin). Researchers discover that CBD causes resistance to insulin, the protein that regulates sugar levels, and increases levels of glucose-dependent insulinotropic peptide (a hormone that ensures adequate release of insulin from digested food) compared to levels before testing started. These results suggest that CBD could be a natural treatment for diabetes by helping the body regulate insulin-related hormone levels.
8. CBD protects against neurological disorders
Preclinical and clinical trials show that CBD has antioxidant and anti-inflammatory properties. Researchers conclude that these features may provide significant neuroprotection, or protection against numerous pathological conditions.
Several preclinical studies suggest that CBD may have beneficial effects against Parkinson’s disease, Alzheimer’s disease and multiple sclerosis. Huntington’s disease and cerebral ischemia have also been studied, however significant positive results are not recorded. Further clinical studies are needed to confirm the benefits of CBD when used as a treatment for these conditions.
9. Inhibiting Arthritis Symptoms
Arthritis is the damage to the tissues in and around the joints. There are different types of arthritis and the symptoms include pain, stiffness and loss of movement. Treatment for arthritis usually focuses on pain relief and improved joint function.
A research from 2006 shows that Sativex – a CBD-based botanical drug approved in the UK in 2010 – promotes statistically significant improvements in sleep quality, pain during movement and pain at rest in patients with rheumatoid arthritis, compared to a placebo. It is the first controlled study with Sativex as a treatment for rheumatoid arthritis, involving 58 patients. CBD has been shown to have an analgesic effect and the ability to suppress disease activity.
In 2018, scientists will enter an investigation towards a more localized treatment, a synthetic CBD gel as a treatment. They do this in doses of 250 milligrams or 500 milligrams per day, or they give a placebo to patients with knee pain due to osteoarthritis. Patients also stop taking other anti-inflammatory drugs or pain relievers, with the exception of acetaminophen, before and during the study period.
The results are interesting, although not entirely convincing. On the one hand, those treated with CBD do not experience much change in pain, compared to the placebo patients. On the other hand, there are statistically significant differences between the group receiving the 250 milligram dose and the placebo group. This becomes apparent when measuring the mean weekly improvement in their worst pain levels and their WOMAC (Western Ontario and McMaster Universities Arthritis Index) physical function assessment. In addition, in this test, men seem to benefit significantly more from CBD than women.
You can read a lot more about CBD HERE on medical cannabis site