- The 400 mg and 800 mg doses of cannabidiol have been shown to be safe and more effective than placebo in reducing cannabis use.
- Cannabis is by far the most widely consumed illicit substance in France.
According to a new study published in The Lancet, CBD, a non-psychotropic component of cannabis, is believed to be effective in freeing users from possible addictive disorders. “The main objective was to identify the most effective dose of cannabidiol to reduce cannabis consumption, explain the researchers. We really need pharmacological treatment for cannabis use disorders. Cannabidiol (CBD) could offer a new medication, but it’s unclear exactly what doses might be safe and effective, “ scientists continue.
200 mg, 400 mg and 800 mg
Between May 28, 2014 and August 12, 2015 (stage one), 48 participants were randomly assigned to a placebo and doses of 200 mg, 400 mg and 800 mg of cannabidiol. In an interim analysis, the 200 mg dose was found to be ineffective. Between May 24, 2016 and January 12, 2017 (second step), randomization continued and 34 additional participants consumed either 400 mg of cannabidiol, 800 mg of cannabidiol or a placebo.
During the experiment, cannabidiol was well tolerated, and no serious side effects were reported in the participants. Finally, “the 400 mg and 800 mg doses of cannabidiol have been shown to be safe and more effective than placebo to reduce cannabis consumption ”, the authors conclude by comparing the times of abstinence.
Diagnosis of addiction
Cannabis is by far the most widely consumed illicit substance in France. In 2016, 42% of adults aged 18 to 64 said they had used cannabis in their lifetime. This experiment, which often for the oldest turns out to be very old, is more the work of men than women (51% against 34%).
The diagnosis of addiction (or dependence) is based on well-defined criteria, set by international mental health bodies and listed in a manual, the Diagnostic and Statistical manual of Mental disorders (DSM), the fifth edition of which dates from 2013. Among these criteria, we find the loss of self-control, the interference of consumption on school or professional activities, or the continuation of consumption despite awareness of the disorders it causes.