Health Coronavirus in Spain: outbreaks, cases and deaths | ...

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According to signature Alfredo Corell, Professor of Immunology at the University of Valladolid, the immune system is “a very complex network of cells and different molecules that are interconnected with each other”, and fight against external threats, “pathogenic microorganisms, pollen grains or food components, cancers or transplantation”. And also against the coronavirus.

But there is more, the zero level, “that separates the interior from the exterior”, with the skin as the protagonist. It is the largest organ in the human body, lining the respiratory system, the digestive system, the eyes or the genitourinary tract. First level, “Innate or natural immunity usually begins when infected cells produce molecules, known as interferons, which warn neighboring cells to paralyze protein production, so that they will be less likely to make new viruses. They alert the defenses and it is essential to kill pathogenic bacteria.

Second line, adaptive or specific immunity. “The most important representatives of this level are the B and T lymphocytes: the T cells are so named because they differ in the thymus and the B cells because they were discovered in the bursa of birds. In humans, however, these cells are differentiate within the bones, in the bone marrow. Both B and T lymphocytes are characterized by a peculiarity, “they recognize infectious agents in a very specific way, comparable to the coupling of a key in a lock: their connection is very, very exact “, has commented the expert.

Regarding SARS-CoV-2, it has been observed that the antibodies disappear a few months after infection, but memory cells may remain, capable of triggering the response if reinfection occurs. “It is very difficult to know how long immunity against SARS-CoV-2 lasts. The pandemic is only a few months old and in many cases only preliminary studies are available. At the moment, however, the antibodies appear to last at least four months. However, in the case of other pathogens, immunity can last for months, years or a lifetime, “he said in ABC.


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