Coronavirus News up to date: THESE 5 factors influence the course of Covid 19

April 14, 2020, 9:02 p.m.

Five factors determine the severity of a Covid 19 disease. Image: AdobeStock / Romolo Tavani

The corona virus still puzzles scientists. Researchers in the United States now want to have found five factors that determine the severity of the course of a Covid 19 disease.

The corona virus keeps the world in suspense. In the meantime, more than 120,000 people worldwide have died from a corona infection. There are currently more than 1.9 million people infected. But there is also positive news: The number of cured patients is increasing day by day. John Hopkins University currently has more than 461,000 healed. (As of April 14, 2020)

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Corona virus continues to puzzle researchers worldwide

As governments continue to stem the spread of the virus, scientists are working hard to research Sars-CoV-2. It’s not just about a drug against Covid-19 or a vaccine against the coronavirus To find the course of a Covid-19 disease, the experts want to understand, in order to draw conclusions for the treatment of patients and to identify risk groups and protect them.

Scientists discover five factors for the severity of Covid-19 disease

As “Focus Online” currently reports, the microbiologist Arturo Casadevall from the Bloomberg School of Public Health at Johns Hopkins University and the infectiologist Liise-anne Pirofski from the Albert Einstein College of Medicine in New York apparently managed to find five factors, which determine the severity of the course of a Covid-19 disease. The scientists have published their results on the “Bloomberg” internet portal.

How many infectious agents has a corona patient ingested?

The course of a coronavirus infection therefore depends on the virus dose, the genetics, the infection path, the virulence of SARS-CoV-2 and the immune status. The Virus dose is explained relatively simply: How many infectious agents has a corona patient ingested? If he has ingested more pathogens, the disease is worse than if he has ingested a low dose. Then a patient can either remain symptom-free or only go through a mild course.

Genetics determine the severity of the coronavirus infection

Also the genetics affects the course, depending on how the protein structure in the cells of the corona patient looks. As is well known, the corona virus docks onto existing cells and affects the tissue. “If the receptors required for a virus are missing, the person affected is resistant to the infection. One example is the HI virus that causes AIDS,” explains “Focus Online”.

How did a Covid 19 patient become infected?

The factor “Infection path” Pirofski and Casadevall also determined the severity of the course of a Covid 19 disease. It makes a difference whether you become infected by inhaling droplets containing viruses or by touching a contaminated surface and then touching your face. With “Virulence of SARS-CoV-2” is the contagion and strength of the virus. This varies enormously within a virus strain.

Previous infections determine the course of a Covid 19 disease

The last deciding factor is that Immune status of the coronavirus patient. According to “Focus Online”, this depends on “previous infections”. “If the immune system has no memory of an infectious agent, it may be unable to react quickly,” write Casadevall and Pirofski. “This helps the intruder escape detection and cause longer damage.” In other words, if I have already had the flu, my body reacts to the coronavirus in a very different way than that of a patient who has not yet contracted the flu.

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