Constance Wu scored Golden Globe best lead actress nomination, the first Asian woman in 44 years to be named in the category.
Wu, who was nominated for her role in Crazy Rich Asians, said she was "ecstatic but also in shock".
The Hollywood film, also won a nomination for best film musical or comedy.
It has so far made around $ 238m (£ 186m) worldwide since its premiere in August.
The film's director, Jon M Chu, tweeted that the twin nominations were the "proudest moment of [his] career. "
Wu is competing with four other actresses for the title of the best actress in a film musical or comedy.
Yvonne Elliman, who was nominated for her role in "Jesus Christ Superstar" in 1974, according to the Hollywood Foreign Press Association, speaking to CNN.
Wu said she "did not think" she would be nominated.
"I'd never seen it an American woman before," she told entertainment. "I know I did not think [it would happen to me]. "
Author Kevin Kwan, whose book was adapted into the movie, also congratulated Wu and the cast on the "historic nomination".
The movie tells the story of an Asian-American woman who gets a culture shock meeting her boyfriend's ultra-wealthy family in Singapore.
It was lauded by many and considered to be a big win for Asian-American representation in Hollywood.