Health Government approves an ISCIII call, for 25.8 million, for...

Government approves an ISCIII call, for 25.8 million, for Precision Medicine projects


The Council of Ministers has given the green light to a call from the Carlos III Health Institute (ISCIII), for an amount of 25.8 million euros, for projects developed in the field of Precision Medicine.

As explained by the Government spokesperson, María Jesús Montero, the commitment to this type of innovative medicine that allows an “individualized” response to citizens is one of the “priorities” of the Executive and was contemplated in the Shock Plan for Science and Innovation.

In fact, it is about the implementation of the Precision Medicine Infrastructure associated with Science and Technology (IMPaCT), the first step of the new Spanish Strategy for Personalized Medicine reflected in the Shock Plan for Science and Innovation presented in July.

Three programs will be subsidized. The first is entitled ‘Predictive Medicine’, aimed at the design and implementation of a large population cohort with clinical, epidemiological and biological data, measured at the individual level, which allows representing the entire population resident in Spain, including the ethnic variability and geographic and environmental diversity.

The idea is to generate a record of individual and population data that is the basis for better decision-making in health; It will allow building predictive models of disease, identifying health inequalities, monitoring key indicators and evaluating the impact of health policies.

The second is the ‘Data Science Program’, which seeks to develop a system for the collection, integration and analysis of clinical and molecular data aimed at improving the health of each individual patient, and which allows the secondary use of existing information in the National Health System for the benefit of society with objectives of public health, health planning and research.

Its objective is to optimize the management of the information generated, to interpret and apply it in the most effective way for the population and the health system; will provide bioinformatics tools for the management of genomic data and medical informatics solutions for the management and integration of clinical data, facilitating the interoperability of the clinical information systems of the different regional health systems.

Finally, the third program, ‘Genomic Medicine’, will develop coordination infrastructures and protocols to carry out genomic analyzes and other ‘omics’ data in an effective, efficient and equitable accessible manner throughout the national territory, taking as support large research centers Spaniards that already have state-of-the-art sequencing technology and experience in its application to the diagnosis of human diseases.

Its purpose is to guarantee a strategic state reserve of very complex diagnostic sequencing services, which will be provided at no economic cost to patients or regional health services; It will optimize and strengthen the available massive sequencing capacities, orienting them to the needs of genetic diagnosis – exomes, complete genomes – and paying special attention to the early molecular diagnosis of rare diseases.

Entities and institutions that carry out or manage R + D + I activities in Biomedicine or in Health Sciences and Technologies can benefit from this call, such as accredited health research institutes, public and private non-profit health entities and institutions linked or arranged with the National Health System, Public Research Bodies, universities and other R&D centers.

Interested entities may request the coordination of one of the three programs of the call, for which they will present a proposal for an Action Plan, as well as the list of collaborating entities that will participate together with the applicant entity and the resources and infrastructures that they contribute. . One project per program will be awarded.

The organization and processes of IMPaCT must conform to the principles of Responsible Research and Innovation (RRI) and Open Science, specifically incorporating principles of responsible governance, ethics, gender equality, scientific education, open access and citizen participation.

In short, this call will make it possible to configure an infrastructure of scientific-technical services that supports and strengthens the existing R & D & I capacities in Precision Medicine and facilitates the real implementation of Precision Medicine in the National Health System.

Likewise, it will allow to generate the capacity for immediate analysis of data obtained in real time, to give a coordinated and immediate response to any scientific emergency that affects Public Health, and to guide research towards health problems through implementation Real of Precision Medicine in the SNS. It will also enhance the participation and leadership of Spain in international R & D & I projects, programs, platforms and infrastructures aimed at Precision Medicine and data science.


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