Heart attack drug could also treat stroke, study finds

The research (New window) (in English) ran for two years and was co-directed by Dr. Bijoy Menon, professor at the University of Calgary and neurologist at Foothills Hospital. the Sunnybrook Health Sciences Centre and the University of Toronto also contributed.

Based on results of clinical trial with 1,600 patients, largest stroke clinical trial ever in Canada, tenecteplase appears to be effective for its treatment. A stroke occurs when blood flow in an artery in the brain is blocked by a blood clot.

Dr. Bijoy Menon explains that Alteplase, which is the drug commonly used to treat stroke, is certainly effective, but more difficult to administer. Its administration can take up to an hour and requires an infusion pump which, moreover, must be monitored. While tenecteplase is simply administered intravenously and with almost immediate effect on the patient, he says.

The ease and speed with which this drug can be administered, in large hospitals, in rural hospitals, in ambulances constitute its great advantage, because, when it comes to save brain cellssame seconds count enormously, points out Dr. Menon.

Et when you treat your patients faster, they tend to do better, and it saves liveshe adds.

In addition to being likely to revolutionize the treatment of strokethe new drug could also be a lower-cost option in middle- and low-income countries, notes Dr Menon.

Tenecteplase has been marketed in Canada since 2001 under the name Tnkase, we can also read on the Health Canada website.

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Testimony of a stroke victim

André Lavoie is 60 years old and lives in Calgary. He agreed to be part of a focus group run by the Cumming School of Medicine from the University of Calgary, as part of a large study of use for stroke patients of a medicinal product authorized for cardiac treatment.

In 2015, he was helping his wife put groceries away when a tin can slipped from her and fell to the ground. I bent down to pick it up with my left arm, but couldn’t.he testifies.

Faced with this unexpected situation, he remembers exclaiming: Oh my God! I have a stroke. Fortunately, he explains, I had the presence of mind to go to my wife and ask her to call 911..

André Lavoie was ultimately lucky that the blood clot that was preventing blood flow to his brain cleared up on its own when the ambulance arrived. However, he continues to suffer from the after-effects of this incident, he confides.

According to him, the use of the drug to treat patients suffering from a AVC was a good idea, especially since it is an injection that is easy and quick to administer. In the event of a new strokeI know [désormais] what to askhe said.

Dr Menon says the drug has already been shown to be safe, but it will take several months before it starts being used regularly.

Carol Kenney, the nurse who coordinated the clinical trial, is already getting impatient: We say time is the brain, so the sooner we treat patients, the better.

With information from The Canadian Press

Source: https://ici.radio-canada.ca/nouvelle/1894810/recherche-medecine-neurologie-traitement-alberta-canada.

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