Oxford researchers have identified a gene that doubles the risk of dying from COVID-19 Business

Explains some of the illnesses

Researchers at the University of Oxford have found that a higher-risk version of the gene is unlikely to allow the cells lining the airways and lungs to respond properly to the virus.

November 4 In Nature Genetics research it is estimated that about 60% have this version of the gene. people from South Asia, compared to 15%. people of European descent.

The results of the study help explain why higher rates of hospitalization and deaths may have been observed in certain communities and in the Indian subcontinent.

The authors warned that the gene could not be used as the sole explanation because many other factors, such as socioeconomic conditions, play an important role. Despite the significant effects of the virus on people of Afro-Caribbean origin, only 2% they have a higher risk genotype.

Used artificial intelligence

The authors said vaccination would be especially beneficial for people with a gene called LZTFL1, as vaccination remains the best way to protect themselves. The results obtained provide an opportunity to conduct studies related to the treatment of patients with this gene, as there are currently no specially formulated drugs.

This “shows how important the lungs respond to the infection,” said James Davies, an associate professor of oxford genomics at the intensive care unit during the pandemic, according to Bloomberg. “This is important because most treatments have focused on how the immune system responds to the virus.”

123RF.com nuotr./Koronavirusas

Davis and his colleagues found the gene using artificial intelligence and state-of-the-art molecular technology. The team learned an algorithm to analyze large amounts of genetic data from hundreds of species of cells throughout the body, and then used a new method that allowed them to find the DNA behind this particular genetic signal.

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All other things being equal, “if you have a higher-risk genotype and feel very unwell about COVID-19, it is 50 percent. “This is unlikely to happen if you had a lower-risk genotype,” Davis told a news conference.


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