Physical activity alleviates the genetic risk of obesity


After fruits and vegetables, it is the physical activity that reveals its fabulous epigenetic potential in the fight against the expression of genes that predispose to obesity.

Our environment has an effect on the expression of our cells. The nucleus of the cell is "…" data-url = "/ health / definitions / genetics-gene-151 /" data-more = "Read more" >genes. This is called epigenetics. Some behaviors promote or inhibit the expression of various genes. Diet is an enormous path for our genes, just as the theories of activity established by physics are applied in well-defined frameworks.
The physics … "data-image =" "data-url =" / sciences / definitions / Physics-Physics-15839 / "Data-more =" Read more ">physical. A team of Taiwanese researchers has just highlighted an attenuation of the expression of the genes associated withobesity through a regular and prolonged physical activity.

The effect of sport in the heart of our genes

Doctors always suggest – or almost – people with chronic metabolic disease do more sports. Especially if we are in the causes and consequences of being overweight
Overweight is an accumulation of fat in adipose tissue. It is often caused by too many calories, … "data-image =" -business- images.jpg "data-url =" / health / definitions / medicina-sovrappeso-15563 / "data-more =" Read more ">overweight or obesity. If this advice is often given in order to increase a person's energy expenditure and calorie consumption, we now know that the effects are beneficial there are many more : Prevention is based on eliminating negative disturbances or reducing their … "data-image =" / 7/0 / 070bdc60f3_50035320_amenagement-prevent-flood-clive-perrin-geograph-cc-2.jpg "data-url =" / planet / definitions / sustainable-development-prevention-6509 / "data-more =" Read more ">prevention many diseases, adjuvants of the treatments of some of them also to reduce the examples of symptoms
Symptoms can affect several organs:

muscle aches, joint pains, headaches, digestive problems, … "data-image =" 8 / e882bacd5b_96032_symptome-woman-mal-head.jpg "data-url =" / health / definitions / medicine-symptom-834 / "data-more =" Read more ">symptoms and improving the quality of life, fighting depression, increasing the body's overall energy expenditure in the short and long term, improving psychological well-being, etc. You could almost risk saying that having a healthy relationship with sport serves as an elixir of youth.

This group of Taiwanese scientists then conducted the study with a methodology similar to that which ended with a strong epigenetic action of fruits and vegetables on the genes associated with obesity: they created a score genetic taking into account the physical activity (intensity and is generally a temporal frequency f, connected to the period T (expressed in s) of the phenomenon observed by the following formula: f = 1 / T.
It is also possible … "data-url =" / sciences / definitions / physics-frequency-3940 / "data-more =" Read more ">frequency), thebody mass index (BMI), waist circumference and hip circumference. Similarly to the fruit and vegetable study, the investigators found that physical activity significantly inhibited the expression of the genes associated with obesity and that it was even more effective for predisposed individuals.

How to induce these behaviors?

This is a very important question you had was obscured in the previous article (see below). While it is easy to advise people to eat more vegetables and do more sports, it is less obvious to actually induce these behaviors. It is in particular the role of behavioral sciences (neuroscience, neuropsychology, behavioral psychology, cognitive and meta-cognitive sciences, etc.). To pose this type of question.

lately, a study he suggested taking action based on direct behaviors (dish size or food supply pragmatism) to encourage people to eat well. These studies focus on trills Which literally means "pushing". These are little things that push people into a population to adopt a certain behavior. If they are already widely used in economics and marketing, their use in the field of public health begins to be effective. The grand opening of gyms and also the economic affordability of this last seems to contribute to an increase in overall physical activity.

What to remember

  • Obesity is a complex disease influenced by genes and the environment.
  • The consumption of fruits and vegetables and physical activity may limit the "genetic" weight gain
  • Fruits and vegetables should be consumed more and physical activity practiced regardless of your state of health.

Obesity: genetics countered by the consumption of fruit and vegetables

Article by Julien Hernandez, published July 17, 2019

Eating lots of fruits and vegetables could allow people who are genetically predisposed to become obese not to.

Genetics, nutrition, non-existent physical activity, stress psychological, pollutants, environment, socio-economic and cultural conditions, food offers… It would be possible to continue the list again. An infinite number of causes can determine obesity which is a complex disease. If we can't do much on the genetic side, we have the power to do soact on our diet and, therefore, to generate useful epigenetic actions.

Food, the best remedy

in this study appeared in L & # 39; American Journal of Clinical Nutrition, an international team of researchers wanted to know the impact of increasing fruit and vegetable consumption on people genetically predisposed to become obese.

Scientists created a genetic risk score using target genes and 77 body mass index (IMC) partner. The score can therefore vary from 0 to 154, each point represents a allele at risk. The higher the score, the greater the risk of developing obesity.

Subsequently, investigators observed the evolution of this second score consumption of fruit and vegetables Historically, a Roman legion had ten cohorts numbered I to X. © Peter Bernik, Shutterstock
Cohort study
A study of … "data-image =" "data-url =" / salute / definitions / medecine-cohorte-15863 / "data-more =" Read more ">cohort American population of over 13,000 people every 5 years, for 20 years. It turned out that the people who had the highest risk level were those for whom they were high fruits and vegetables had the greatest effect on weight gain and BMI.

Other things being equal, the observed benefits were greater for the consumption of berries, citrus fruits and green leafy vegetables. The reduction in genetic risk was independent of the fiber content or the glycemic load of the plants. Whether you are obese or overweight, consumption fruit and vegetables should be the mainstay of your diet. This study is only pushing a little bit more by nailing the hammer that the consumption of the latter can only be beneficial – even saving – for health.

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Our second brain responsible for obesity? Raphael Moriez, a neurobiologist at the University of Nantes, explains the link he has just discovered with his colleagues between the enteric nervous system, also called "second brain" and obesity. © Inserm

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