A consortium of Louisiana scientists from the Pennington Biomedical Research Center of LSU, Tulane University and Mary Bird Perkins Cancer Center aims to find out how early blood sugar levels contribute to the brain health of a person in middle age.
These results could lead to new guidelines for managing blood sugar for children and help prevent late cognitive decline – a condition for which there is no effective treatment.
"The study of the heart of Bogalusa is one of the longest and most ongoing studies on a semi-rural biracial community in the South. It is the only study that has collected assessments of the metabolic status of community members from early childhood to middle age "says Dr. Owen Carmichael, co-principal researcher and director of the Biomedical Imaging Center at Pennington Biomedical. "This study will add measurements of brain health and cognitive performance in middle age."
Carmichael and colleagues will use positron emission tomography (PET) and magnetic resonance imaging (MRI) to assess brain health in study participants.
In addition to being a cancer treatment center, Mary Bird Perkins has unique expertise with imaging technologies that can also enable brain health assessment. About 200 volunteers from Bogalusa Heart Study will receive PET scans at the Mary Bird Perkins facility in Hammond, according to Jonas Fontenot, PhD, Chief Operating Officer and Chief of Physics at Mary Bird Perkins Cancer Center and study co-investigator.
"We are excited to play a role by offering advanced imaging services for this important research," says Dr. Fontenot. "This is a collaboration that we hope will inform future health care decisions and impact disease prevention. As an organization, we continue to look for ways to advance medicine and collaborate with similar institutions dedicated to improving health care in Louisiana. ".
"These imaging data will be linked to the same blood glucose levels of the participants during their childhood years in the study of the heart of Bogalusa," adds the co-investigative co-director of Lydia Bazzano, MD, PhD.
Biostatistic tests will then be used to determine if there is a relationship between blood sugar levels, experienced volunteer volunteers and markers of brain health – including markers of Alzheimer's disease – measured by PET and MRI in the middle age.
The study is officially entitled "The glycemic state of early childhood and the neuroimaging indicators of Alzheimer's disease in the Middle Ages: the study of the heart of Bogalusa". The short version of the title is The Bogalusa Heart Study – Brain 2 or BHS – Brain 2. The study should start recruiting on May 15th.
Published in: News on children's health | Medical science news | Medical research news | Medical condition news
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