A genetic study reveals the secrets of parasitic worms and their possible treatments. Today's newspaper, citing Al-Sabah Al-Arabi, publishes a genetic study that reveals the secrets of parasitic worms and their possible treatments. The genetic study reveals the secrets of parasitic worms and their possible treatments. Reveal the secrets of parasitic worms and their possible treatments.
Today, the largest study so far on the genetic composition of helminths has shown hundreds of new evidence of how to invade the human body, avoid its immune system and cause disease.
The findings suggest potential treatments to get rid of these worms to help combat some of the most neglected tropical diseases, including river blindness, bilharzia and ancelostoma, affecting around a billion people worldwide.
"Parasitic worms are some of our oldest enemies and have evolved over millions of years to gain considerable experience in the manipulation of the immune system," said Mikdunka Mitreva of the McDonnell Institute of Genome at the University of Washington, who co-directed the research work with colleagues at the Wellcome Sanger Institute at the University of Edinburgh.
The results of this study will lead to a more in-depth understanding of parasite life and a greater understanding of how the human immune system is used and controlled.
Parasitic infections can persist for many years and cause severe pain, physical disabilities, delayed growth in children and a social stigma associated with deformity.
Current drugs, including drugs developed by Sanofi and Johnson & Johnson, can have little effect and are often claimed by pharmaceutical companies or sold at a low cost to those in need. But the range of drugs that treat wormworm is still limited.
To try to improve drug development and understand how worms invade human bodies and animals and animals, the research team compared the genetic map of up to 81 types of round and flat worms, 45 of which have never been genetically modified .
The analysis detected about 1 million new genes belonging to thousands of new genetic families and identified many potential drugs.
The results were published in the journal Nature Genetics on Monday.
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source: Arab morning