Certain conditions worsen the symptoms associated with Coivd-19. What conditions are affected?
[UpdatedMay222020[Misàjourle22mai2020at 4:40 p.m.]Since the start of the Covid-19 epidemic, the government has warned those at “risk” against potential complications related to SARS-CoV-2. Statistics from Santé Publique France (from 16 mas to 17 May 2020) allow a profile to be established: 73% of intensive care patients are men and 54% of intensive care patients (ICU) are over 65 years of age. 77% of ICU patients have at least one comorbidity. Among the aggravating pathologies of patients in intensive care, there are: obesity – overweight at 33%, diabetes at 25%, cardiac pathologies at 19% and pulmonary pathologies at 16%. In addition, a third of the patients who died in the ICU were diabetic and another third presented with cardiac pathologies.
One of the most “at risk” audiences according to statistics compiled by Santé publique France on the coronavirus epidemic is the population over 60 years of age. The 10,308 deaths recorded in nursing homes since the beginning of March attest to this. According to the epidemiological point published on May 21, 2020 by Santé publique France, 54% of intensive care patients were over 65 years of age. In addition, deaths without co-morbidity, in other words without other pathology, concerned almost all people over 70 years of age. The median age of victims is 72 years and 38% were aged 75 years and over.
The chronically ill are considered “at risk” by the government. The latest epidemiological assessment shows that 77% of Covid + patients in intensive care have co-morbidities. An Italian study confirms these French figures: out of 1,290 deaths from coronavirus, 61.9% had more than three co-morbidities. The most common condition is high blood pressure (73% of subjects). Followed by type 2 diabetes (31.5%) and ischemic heart disease (28.1%).
“All resuscitation in France finds a very large proportion of overweight or obese patients,” said Dr. Matthieu Schmidt, from the Pitié-Salpêtrière hospital in Paris, to AFP. According to Public Health France data, 33% of intensive care patients are overweight or obese. Olivier Ziegler, endocrinologist and nutritionist at the CHRU of Nancy indicated on RMC: “There is a dose effect. The more the corpulence increases, the more the risk of being intubated and ventilated increases”. This fragility is explained by the restricted respiratory capacities of people suffering from obesity. Obese people get out of breath more quickly, so their lungs are weakened and their immune system is weakened. De facto, their organizations find it more difficult to fight Covid-19.
According to Covid-19 statistics, the disease killed 25% of women against 75% of men. Professor Pialoux reported on BFMTV that the ratio of people hospitalized in intensive care was 7 men for 3 women. He hypothesized: “There is probably an enzyme whose gene on the X chromosome is used to get the virus into the cells.” Professor Pierre Delobel, head of the infectious diseases department at the Toulouse University Hospital, said: “Innate immunity is better in women, especially before menopause.”
A study published in the medical journal News England Journal of Medicine, found that the risk for smokers to develop a severe form of the coronavirus is increased by 50% and the risk of death increases by 130% compared to non-smokers. However, the caregivers are surprised at the reality on the ground. “There is something very special about tobacco. We have found that the vast majority of serious cases are not smokers, as if […] tobacco protected against this virus, via nicotine, “said Professor Delfraissy.
However, the National Committee against smoking (CNTC) has warned: “smokers are at increased risk of contracting [le coronavirus] and develop a severe form. “The organization recalled that it is essential to smoke outside” in order to avoid passive smoking “risk factor for acute and chronic respiratory infections in children.”
The blood group
A Chinese study reported that our blood group could be a determining factor in the transmission of the virus. The study, published on the MedRxiv site, relates to 2,100 people affected by the virus and hospitalized in 3 hospitals in Wuhan and Shenzhen. It indicates that people in the O blood group are 33% less likely to be infected with the coronavirus. Conversely, groups A are more vulnerable, with 20% more risk of being contaminated. Group B would also be more affected than the average, but the authors consider that the sample is too small to establish it statistically. The study links blood groups to antibodies, ensuring that people in group O would be better equipped to deal with the coronavirus. However, the authors called for caution and encouraged further studies.
In a column published in Le Parisien, a hundred psychiatrists worried about the fate of the 12 million people suffering from mental disorders. Indeed, this audience is fragile. “They are exposed to a more serious Covid because they are twice as carriers of chronic diseases that we talk about all the time, diabetes, cardiovascular disease, obesity,” explained on FranceInfo Marion Leboyer, professor of psychiatry at Paris-Est Créteil University.