What's happening with Nolotil?

Very used in Spain, this analgesic and antipyretic has fallen out of favor after adverse reactions have been reported in British patients

Health recommends that you do not use medicines that contain Metamizol (the best known is Nolotil). (Photo: Europa Press)

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "The & # 39; Metamizol & # 39; is one of the more analgesics consumed in Spain, a medicine that is much better known by its first trade name, nolotil, although at the moment there are many generic versions that coexist with the original. "data-reactid =" 32 ">" Metamizol "is one of the most commonly used analgesics in Spain, a medicine that is much better known by its trade name, nolotil, although at the moment there are many generic versions that coexist with the original.

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "It is sold with a prescription and its use has doubled in the last 10 years, although the most marked increase occurred in the last 5 (in 2013 and 2017 respectively 14.6 and 22.8 million capsules were dispensed), according to the data prescribed by the National Health System. "data-reactid =" 33 "> It is sold with a prescription and its use has doubled in the last 10 years, although the most marked increase occurred in the last 5 (in 2013 and 2017 respectively 14.6 and 22.8 million capsules were dispensed), according to the data prescribed by the National Health System.

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "The package leaflet of this medicine ensures that agranulocytosis is an effect collateral "Very strange" what would happen in one in 10,000 patients. However, in Spain The sale of Nolotil to tourists was "banned" if linked to the death of 10 British citizens. A ban, which according to the publication The Spanish, It could be 10 years of delay as a 2009 study warned of the risk of adverse effects on British citizens.
"data-reactid =" 34 "> The package leaflet of this drug ensures that agranulocytosis is a side effect "Very strange" what would happen in one in 10,000 patients. However, in Spain The sale of Nolotil to tourists was "banned" if linked to the death of 10 British citizens. A ban, which according to the publication The Spanish, It could be 10 years of delay as a 2009 study warned of the risk of adverse effects on British citizens.

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Spanish Agency for Medicines and Health Products (AEMPS)) not officially recognizes this report but recommends that doctors only prescribe this drug for short treatments (maximum seven days) and not foreigners. The alarm is blown later denunciation of a translator of Jávea (Alicante), presented by The Times, which has done its particular research after discovering that several English patients who had attended in his medical consultations had suffered a fatal adverse reaction."data-reactid =" 35 "> The Spanish Agency for Medicines and Health Products (AEMPS) does not officially recognize this report, but recommends that doctors only prescribe this medicine for short treatments (maximum seven days) and not foreigners. The alarm is blown later denunciation of a translator of Jávea (Alicante), presented by The Times, which has done its particular research after discovering that several English patients who had attended in his medical consultations had suffered a fatal adverse reaction.

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Given this, clarify the AEMPS, and to "The recent notification to the Spanish pharmacovigilance system of agranulocytosis cases, in particular in patients of British origin" it was decided to discourage the prescription of this drug. He also influenced the decision that the doctors can not trace or perform checks in the floating population (tourists). "data-reactid =" 52 "> Faced with this fact, clarifies AEMPS, and due to "The recent notification to the Spanish pharmacovigilance system of agranulocytosis cases, in particular in patients of British origin" it was decided to discourage the prescription of this drug. He also influenced the decision that the doctors can not trace or perform checks in the floating population (tourists).

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Agranulocytosis or neutropenia"data-reactid =" 53 ">Agranulocytosis or neutropenia

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "This reaction causes an acute decrease in the blood of a type of white blood cells, granulocytes, which predispose the body to contract infections and cause a severe reaction that can lead to the patient's death, after lowering their defenses and the subsequent development of sepsis or multiple infections. This is the pathology suffered by English patients who have reacted to the Ministry of Health. "Data-reactid =" 54 "> This reaction causes an acute decrease in the blood of a type of white blood cells, granulocytes, which predisposes the body to infection, and causing a severe reaction that can lead to the patient's death, after lowering their defenses and the subsequent development of sepsis or multiple infections. This is the pathology suffered by the English patients who reacted to the Ministry of Health.

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "But it's not something new, the relationship between Metamizol and agranulocytosis has been documented since the 1970s. Although studies indicate a greater susceptibility of the population of Northern Europe, experts believe that you can not "Nor discard or confirm a greater ethnic risk". "data-reactid =" 55 "> But this is not something new, the relationship between Metamizol and agranulocytosis has been documented since the 1970s. Although studies indicate a greater susceptibility of the population of Northern Europe, experts believe that you can not "Nor discard or confirm a greater ethnic risk".

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "What is known with certainty is that it appears more often in elderly patients e when the duration of treatment is longer than a week. They also warn that it is necessary to immediately stop taking in case of signs or symptoms indicative of said adverse reaction. In any case, we must reiterate it It is not a frequent adverse effect, and there are other drugs that can also produce it, according to the doctor in pharmacy Marián Garcia, who qualifies him "A good use of drugs by everyone (doctors, pharmacists and patients) minimizes risks"."data-reactid =" 56 "> What is known with certainty is that it appears more frequently in patients of advanced age and when the duration of treatment is longer than a week. They also warn that it is necessary to immediately stop taking in case of signs or symptoms indicative of said adverse reaction. In any case, we must reiterate it It is not a frequent adverse effect, and there are other drugs that can also produce it, according to the doctor in pharmacy Marián Garcia, who qualifies him "A good use of drugs by everyone (doctors, pharmacists and patients) minimizes risks".

English, Irish and Scandinavia are worse; but if it is well planned, it is rare for it to affect the Spanish population. That's why it had not been banned until now. (Photo: Getty)

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "What is it for?"data-reactid =" 81 ">What is it for?

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = " Doctor Paulino Cubero, family doctor, he told Cadena Ser that "in Spain it is used massively, even in very high doses ", but highlights his safety although in other European countries it is not marketed due to the side effects attributed to it. "data-reactid =" 82 "> El Doctor Paulino Cubero, family doctor, he told Cadena Ser that "in Spain it is used massively, even in very high doses ", but highlights his safety although in other European countries it is not marketed due to the secondary effects attributed to it.

<p class = "canvas-text canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Nolotil is recommended for colic, pains oncological and internal, postsurgical, dental, fever this does not happen with other antipyretics; It has a good digestive tolerance. "Data-reactid =" 83 "> Nolotil is recommended for colic, pains oncological and internal, postsurgical, dental, fever this does not happen with other antipyretics; It has a good digestive tolerance.

<p class = "canvas-text canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "The normals are 575 milligram capsules, although it is common in Spain to use vials of 2 grams (a very high dose) which, in the opinion of this general practitioner, should be used with "More care"."data-reactid =" 86 "> The normals are i 575 milligram capsules, although it is common in Spain to use vials of 2 grams (a very high dose) which, in the opinion of this general practitioner, should be used with "More care".

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "As mentioned, they are attributed blood changes, potentially fatal agranulocytosis (destruction of white blood cells). In fact, in the United States and the United Kingdom it is not marketed. "Data-reactid =" 89 "> As we said, they were attributed blood changes, potentially fatal agranulocytosis (destruction of white blood cells). In fact, in the United States and the United Kingdom it is not marketed.

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