Persistent asthma damages the cardiovascular system
In a new study involving experts from University of Washington was examined whether persistent asthma with the deposition of plaques in the carotid artery (carotid arteries). The results are in the “Journal of the American Heart Association” released.
Data from the MESA study were evaluated
The team used data from Multi-Ethnic Study of Atherosclerosis (MESA), which included almost 7,000 participants who started the course no cardiovascular diseases had.
In the current study, the researchers used the data from 5,029 participants evaluated, who were on average 61 years old and at the onset Risk factors for cardiovascular disease were found. Ultrasound data of the carotid artery were also available for all participants and 53 percent were women.
The participants were divided into three different categories: People with persistent Asthmaintermittent asthma and no asthma. 109 participants fell into the subgroup with persistent asthma, 388 participants into the subgroup with intermittent asthma and the remaining participants had no asthma.
Plaques measured in the carotid artery
At the start of the MESA study, ultrasound scans of the left and right carotid arteries to identify plaques in the carotid artery. The researchers explain that, based on the number of plaques in the walls of both carotid arteries, a total value of the load was calculated.
In addition, blood levels of inflammatory biomarkers were also identified Interleukin-6 (IL-6) and C-reactive protein (CRP), the researchers add.
Carotid artery deposits widespread
The data analysis showed that 67 percent of participants with persistent asthma had plaques in the carotid artery, while this was only the case for 49.5 percent of people with intermittent asthma and for 50.5 percent of participants without asthma.
In addition, people with persistent asthma who had deposits in the carotid artery had an average of two plaques, while the other groups had an average of just one plaque.
Risk doubled in persistent asthma
After the data had been adjusted for possible influencing factors such as age, gender, weight, use of prescription drugs or smoking, participants were included persistent asthma compared to people without asthma, almost twice as high Likelihood of plaques in their carotid arteries, according to the research team.
In addition, participants with persistent asthma reported higher values inflammatory biomarkers on. “Participants with persistent asthma had elevated blood levels of inflammation even though their asthma was being treated with medication, underscoring the inflammatory characteristics of asthma‘ explains the author of the study Matthew C. Tattersall in a press release der American Heart Association.
„This analysis tells us that the increased risk of carotid plaques in people with persistent asthma is likely influenced by multiple factors“, so Tattersall. It is also known that higher levels of inflammation lead to negative effects on the cardiovascular system.
„Many doctors and patients are unaware that the inflammation in the airways in asthma can affect the arteries“, emphasizes Tattersall. In more severe forms of asthma, treatment of cardiovascular risk factors by adjusting the lifestyle and diet therefore make a special contribution to prevention. (as)
Author and source information
This text corresponds to the specifications of medical specialist literature, medical guidelines and current studies and has been checked by medical professionals.
- Matthew C. Tattersall, Alison S. Dasiewicz, Robyn L. McClelland, Nizar N. Jarjour, Claudia E. Korcarz, et al.: Persistent Asthma Is Associated With Carotid Plaque in MESA; in: Journal of the American Heart Association (veröffentlicht 23.11.2022), YES
- American Heart Association: Persistent asthma linked to increased buildup of plaque in arteries leading to the brain (veröffentlicht 23.11.2022), American Heart Association
This article contains general advice only and should not be used for self-diagnosis or treatment. He can not substitute a visit at the doctor.