Why the goal of weight loss is essential in the management of type 2 diabetes


  • Obesity is often a driver of type 2 diabetes
  • A weight loss of at least 15% should, according to a study published in The Lancet, be at the heart of the management of this disease

What if 15% weight loss became the primary goal in managing type 2 diabetes? This is what suggests a study conducted by researchers at the University of Texas and published on September 30 in The Lancet. This would have the effect of slowing down, reversing the progression of the disease and its complications.

“We suggest that for most type 2 diabetes patients without cardiovascular disease, the key is to manage the key underlying abnormality and the driving force behind the disease, i.e. obesity,” said the doctor. Dr Lldiko Lingvay, author of this study Such an approach would have the advantage of treating not only hyperglycemia but also other complications related to obesity such as fatty liver, sleep apnea, osteoarthritis and hypertension thus having a greater impact on the overall health of the patient than the simple management of his blood sugar “.

Remission of the disease in 2 years

To reach these conclusions, Dr. Lingvay recalls the results of other studies including the DIRECT trial which evaluated the effects of a lifestyle change in overweight patients with type 2 diabetes for less than 6 years. . This demonstrated disease remission within 2 years in 70% of patients who lost 15 kilograms or more for an average base weight of 100 kilograms. Other work on bariatric surgery has also shown immediate and lasting benefits for obese patients with type 2 diabetes by reducing their need for hypoglycemic drugs in the days following the procedure and improving several long-term health indicators. term.

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A weight loss of at least 15%

The study published in The Lancet states that “the main characteristics identifying people in whom increased body fat is a key factor in type 2 diabetes are the presence of fat around the waist, hypertension, high blood pressure and fatty liver”. Which leads Dr. Lingvay to say that for this population, a total weight loss of at least 15% would improve blood sugar control but above all prevent the long-term progression of the disease and its complications. associated metabolic processes.

Dr. Lingvay’s work also incorporates recommendations for the follow-up of these obese patients with type 2 diabetes: “It is also essential that medical practice integrates weight management in these patients and that those who treat them acquire health. ‘experience in all aspects of obesity management “.

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