Eric Dane, ‘Grey’s Anatomy’ and ‘Euphoria’ Star, Dies at 53 After ALS Battle

Eric Dane, best known for his role as Dr. Mark Sloan on the hit medical drama “Grey’s Anatomy,” has died at the age of 53 following a battle with amyotrophic lateral sclerosis (ALS). His family announced his death on Thursday, February 19, 2026.

ALS Diagnosis and Advocacy

Dane publicly announced his diagnosis of ALS in April 2025 [CBS News]. Throughout his journey with the disease, he became a passionate advocate for ALS awareness and research, determined to make a difference for others facing the same challenges. He even traveled to Washington, D.C. To meet with lawmakers to advocate for funding [USA Today].

“With heavy hearts, we share that Eric Dane passed on Thursday afternoon following a courageous battle with ALS,” his family said in a statement. “He spent his final days surrounded by dear friends, his devoted wife, and his two beautiful daughters, Billie and Georgia, who were the center of his world.”

The family continued, “Throughout his journey with ALS, Eric became a passionate advocate for awareness and research, determined to make a difference for others facing the same fight. He will be deeply missed, and lovingly remembered always. Eric adored his fans and is forever grateful for the outpouring of love and support he’s received. The family has asked for privacy as they navigate this impossible time.”

Career Highlights

Dane rose to fame playing Dr. Mark Sloan, nicknamed “McSteamy,” on “Grey’s Anatomy” from 2006 to 2012 [NBC News]. His character, the head of plastic surgery, was so popular that the hospital on the show was later renamed after him. He reprised his role in 2021.

More recently, Dane gained recognition for his role as Cal Jacobs in HBO’s drama series “Euphoria” in 2019 [AP News]. He was set to appear in the show’s final season this year.

Dane’s career spanned decades, with roles in films such as “X-Men: Last Stand” and “Marley & Me.”

Personal Life

Born in 1972, Dane was raised in Northern California. His father, a Navy veteran and architect, died when Dane was seven years traditional. He moved to Los Angeles after high school and began his acting career with roles in shows like “Saved by the Bell.”

He is survived by his wife, actress Rebecca Gayheart, and their two daughters, Billie and Georgia.

Understanding ALS

ALS, also known as Lou Gehrig’s disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord [CBS News]. It impacts a person’s ability to walk, talk, and eventually breathe without assistance. The cause of ALS is unknown, and there is currently no cure. Most patients die within three to five years of diagnosis [CBS News].