Managing Herpes Simplex Virus (HSV) During Pregnancy
Dealing with a herpes simplex virus (HSV) diagnosis while pregnant can be stressful, but it’s crucial to start with the most critical fact: most pregnant women with HSV-2 have normal pregnancies and deliver healthy babies. While the virus poses certain risks, understanding how it spreads and what symptoms to watch for is key to a healthy outcome for both mother and child.
- Most women with HSV-2 deliver healthy babies.
- The most common method of newborn infection is passing through the birth canal.
- HSV-2 is the most frequent cause of genital herpes and newborn infections, though HSV-1 can also occur.
- Disseminated HSV infection in pregnant women can lead to rare complications like hepatitis.
How Newborns Grow Infected
Newborn infants can contract the herpes simplex virus at different stages of the reproductive process. According to MedlinePlus, there are three primary pathways for infection:
- During Labor or Delivery: This is the most common method, where the baby acquires the virus while passing through the birth canal. The risk increases if the mother has an active genital herpes outbreak at the time of delivery, though some women may have sores inside the vagina without knowing it.
- In the Uterus: While unusual, infection can occur during pregnancy.
- After Birth (Postpartum): Infants can contract oral HSV through contact, such as being kissed by someone with cold sores.
Understanding HSV-1 vs. HSV-2
There are two main types of the virus that can affect pregnancy and newborns. HSV type 2 is the most common cause of genital herpes and the most frequent cause of HSV infection in newborn babies. However, HSV type 1, which is more commonly associated with oral herpes, can also cause infections in newborns.
Risks to the Mother and Fetus
While many pregnancies proceed without complication, certain manifestations of the virus carry higher risks.

Disseminated HSV Infection
In some cases, the virus can spread throughout the body, known as disseminated herpes. For pregnant women who acquire HSV during pregnancy, the CDC notes that hepatitis is a rare but reported manifestation of this disseminated infection.
Intrauterine Infection
The risk of intrauterine infection is significantly higher in pregnant women who develop disseminated HSV infections. Research published via PMC indicates that about 50% of these cases result in intrauterine infection, with 90% of those related to HSV.
Recognizing Neonatal Herpes Symptoms
If a newborn is infected, the symptoms can vary based on how far the virus has spread.
Skin Infections
In mild cases, herpes may only appear as a skin infection. This typically manifests as tiny, fluid-filled blisters called vesicles. These blisters eventually break, crust over, and heal, sometimes leaving a mild scar.
Severe or Disseminated Infection
When HSV spreads to the brain (herpes encephalitis), liver, lungs, or kidneys, the infant becomes extremely sick. These cases may or may not include skin blisters. Warning signs include:
- Respiratory Distress: Rapid breathing, short periods without breathing (apnea), grunting, nostril flaring, or a blue appearance.
- Physical Indicators: Yellow skin and whites of the eyes (jaundice), effortless bleeding, and low body temperature (hypothermia).
- Neurological and Systemic Issues: Seizures, shock, coma, weakness, and poor feeding.
Frequently Asked Questions
Can I have herpes and not know it?
Yes. Some women have had HSV infections in the past but aren’t aware of them, and others may have active sores inside the vagina that aren’t visible, which can still lead to the virus being passed to the baby during birth.
Is a healthy baby possible with HSV-2?
Absolutely. As noted by the American Sexual Health Association, the vast majority of pregnant women with HSV-2 deliver healthy babies.
Disclaimer: This article is for informational purposes and does not replace professional medical advice. Always consult your healthcare provider for personalized pregnancy care.