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Kyler Hess undergoes living-donor liver transplant for stage 4 cancer

Kyler Hess, a father of four from Polk City, Iowa, has successfully undergone a living-donor liver transplant, marking a turning point in his battle against stage 4 colorectal cancer. The diagnosis, delivered in July 2025, revealed a dire…

Kyler Hess undergoes living-donor liver transplant for stage 4 cancer

Kyler Hess, a father of four from Polk City, Iowa, has successfully undergone a living-donor liver transplant, marking a turning point in his battle against stage 4 colorectal cancer. The diagnosis, delivered in July 2025, revealed a dire situation: initial CT scans identified more than 15 tumors within his liver.

A Stage 4 Diagnosis and a Race Against Time

After an initial assessment by doctors in Des Moines, the Hess family sought specialized care at the Mayo Clinic in Rochester, Minnesota. There, a rigorous combination of medical treatment and nutritional adjustments successfully reduced the tumor burden, opening a window of eligibility for a transplant.

Iowa father with stage 4 colorectal cancer gets liver transplant thanks to surprise donor

The Necessity of a Living Donor

The medical team faced a significant hurdle: Hess’s brother was ruled out as a donor due to his liver anatomy. With the transplant team confirming that a living donor was needed, the family looked for a match. The procedure hinges on the human liver’s unique capacity for regeneration—a single lobe can be transplanted, with the remaining portion in the donor growing back to full size.

A Stranger’s Unexpected Intervention

Help arrived from an unlikely source. Abby Conley, a fellow Polk City resident who did not personally know the Hess family, began the donation process after following Kyler’s health updates online. She underwent three days of testing at the Mayo Clinic to confirm her compatibility.

Conley’s motivation was deeply personal. Her father died in 2021 while awaiting a bone marrow transplant for leukemia. In a letter written before his passing, he described his life as a “fairy tale” and urged his family to carry that legacy forward. By donating to Hess, Conley chose to act on that final encouragement.

Focusing on the Future

Throughout the ordeal, Emilie Hess, Kyler’s wife, kept the family focused on their own narrative rather than the statistical outcomes often associated with stage 4 cancer. For Kyler, the transplant is more than a medical procedure; it is a bridge to the future.

He views the operation as a necessary intervention, one that ensures he can remain a present father. He is now looking ahead to the milestones he once feared he might miss, including his children’s graduations and the significant life events that define their family’s story.

About the author: Dr Natalie Singh - Health Editor

Board‑certified internal‑medicine physician and MPH. Natalie authored peer‑reviewed studies on infectious disease and served as medical editor. “Dr. Natalie Singh delivers evidence‑based health news, medical breakthroughs, and expert wellness guidance.”