The Rise of ‘Ozempic Face’ and How Celebrities Are Experiencing It

Every other day, a celebrity debuts their dramatic transformation, sparking online discourse about the utilize of weight-loss drugs. As soon as images of a transformed A-lister surface, speculation begins about “Ozempic face,” one of the potential risks of the diabetes medication. Simultaneously, many defend the celebrity, stating their choices are personal or insisting the transformation was natural. However, a common thread remains: many celebrities look noticeably different after using weight-loss medications like Ozempic.

In a 2025 YouTube video, facial plastic surgeon Dr. Donald B. Yoo explained that facial aging signs may become more pronounced after rapid weight loss induced by these drugs. He also described “Ozempic neck,” explaining that rapid weight loss can expose the platysma, a muscle in the neck. “And if your platysma…is sagging, then that sagging is going to show right away,” Dr. Yoo said. Individuals starting these medications in their 40s are generally more likely to experience Ozempic neck, as skin tautness naturally declines with age.

Sharon Osbourne’s Ozempic Journey

During a November 2023 appearance on “Good Morning Britain,” Sharon Osbourne confirmed she used Ozempic for weight loss, stating she was “fed up” with constant fluctuations. In a November 2023 interview with the Daily Mail, Osbourne said she was unbothered by online perceptions of her weight loss but admitted struggling with her self-image after losing 42 pounds in four months. “I’m too gaunt and I can’t put any weight on,” she shared. “I want to, because I sense I’m too skinny. I’m under 100 pounds and I don’t want to be.”

Photos from 2016 and 2025 show a significant loss of fullness around Osbourne’s neck. During an April 2024 podcast appearance on “Howie Mandel Does Stuff,” Osbourne admitted going “too far” with Ozempic and continuing use even after reaching her goal weight, believing it interfered with her metabolism. Despite her own experiences, Osbourne told “Good Morning Britain” she believes the drug is viable for adults who understand its caveats, but younger generations should focus on healthy eating habits.

Rosie O’Donnell’s Surprising Weight Loss with Mounjaro

In a January 2023 TikTok, Rosie O’Donnell revealed her doctor recommended Mounjaro for diabetes. She lost 10 pounds over the holidays, also limiting sugar and prioritizing water. In February 2024, O’Donnell shared a side-by-side comparison on Instagram, showcasing facial volume loss after a year on Mounjaro.

In a March 2025 TikTok, O’Donnell explained that moving to Ireland and cooking her own meals aided her weight loss. She found it “completely shocking” to fit into larger sizes after wearing plus-size clothing. In May 2025, she shared Instagram posts admitting difficulty believing she was the person in the photos, both captioned with the hashtag #Mounjaro. Side-by-side photos from 2019 and 2025 show a loss of fullness in her neck and reduced skin tautness.

Tori Spelling’s Experience with Ozempic and Mounjaro

During an April 2024 episode of the “misSPELLING” podcast, Tori Spelling shared she tried various methods to lose weight after her fifth child in 2017. Her doctor attributed her lack of success to her age (43 at the time). She initially tried Ozempic without success, but saw results when she followed her doctor’s recommendation to use Mounjaro alongside hormonal-regulation medication. Spelling stopped taking the diabetes drug around January 2024 after reaching her goal weight.

Photos from 2021 and 2025 show considerable weight loss around Spelling’s neck, resulting in a more pronounced jawline and visible neck muscles. In a 2009 People interview, Spelling admitted that weight gain from her first two pregnancies impacted her self-esteem. By 2024, she felt confident enough to express zero shame about losing weight with Mounjaro.

Kathy Bates’ Journey and Ozempic’s Role

In an October 2024 interview with People, Kathy Bates shared she lost 80 pounds over seven years through her own efforts, with Ozempic assisting in the final 20 pounds. “There’s been a lot of talk that I just was able to do this because of Ozempic,” she said. “But I have to impress upon people out there that this was hard work for me, especially during the pandemic.”

Bates began focusing on her health after a 2017 type 2 diabetes diagnosis, motivated by her family’s history with the condition. She focused on nutrient-dense foods, reducing emotional eating, and listening to her body’s cues. In a September 2025 Variety interview, Bates addressed critics, stating, “People say, ‘Well, it was the Ozempic.’ F*** you, it was the Ozempic!” Photos from 2015 and 2025 show a gradual weight loss, but Ozempic appears responsible for a significant loss of volume around the neck, beginning around 2023.

Whoopi Goldberg’s Weight Loss Prompted by an Awkward Moment

During a March 2024 episode of “The View,” Whoopi Goldberg revealed that steroids and other solutions hadn’t helped as much as Mounjaro. She emphasized taking responsibility for one’s health, and body. Goldberg shared that someone mistook her for wearing a “fat suit” in her 2022 movie “Till,” prompting self-reflection and the realization she weighed 300 pounds.

Although she didn’t specify the amount of weight lost, she said it was the weight of “two people.” Photos from 2026 show more pronounced neck muscles compared to 2017, with some loss of elasticity due to the drug and natural aging. However, Goldberg seems to be feeling her best.