Updated Dec. 27, 2025, 8:14 a.m. MT
Who will win teh first Saturday game in NFL Week 17?
The Houston Texans adn Los Angeles Chargers play on Saturday, Dec. 27, at the Chargers’ SoFi Stadium in a game on the NFL Week 17 schedule.
What do NFL Week 17 odds say about the game? Who are NFL Week 17 predictions and NFL Week 17 picks taking in the game?
Which team has the best chance to win the game according to NFL Week 17 win probabilities?
Check out the Arizona Republic’s score prediction for the game, as well as Texans vs Chargers picks, odds and win chances for the Dec. 27 NFL Week 17 game, which can be seen at 2:30 p.m. MST on NFL Network (stream on FUBO).
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what channel is Texans vs Chargers on? how to watch NFL Week 17 game Saturday
NFL Week 17 picks: Cowboys at Commanders | Lions at Vikings | Broncos at Chiefs | Texans at Chargers | Ravens at Packers | Seahawks at panthers | Cardinals at Bengals | Steelers at Browns | Jaguars at Colts | buccaneers at Dolphins | Patriots at Jets | Saints at Titans | Giants at Raiders | Eagles at Bills | Bears at 49ers | Rams at Falcons | The Republic’s score predictions
Chargers are a 2-point favorite over the Texans in NFL Week 17 odds for the game, courtesy of BetMGM Sportsbook.
Los Angeles is -130 on the moneyline, while Houston is +110.
The over/under (point total) is set at 39.5 points.
NFL Week 17 odds: Point spreads, moneylines, over/unders for betting
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Reach Jeremy cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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