Chrissy Metz revealed her 100-pound weight loss and discussed the physical and mental benefits of using a GLP-1 while making her Broadway debut in & Juliet, Page Six reported. The 45-year-old actress attended the Nocturne premiere over the weekend wearing a green velvet gown, where she detailed how the treatment has aided her stamina during rigorous eight-show-a-week theater schedules.
According to Entertainment Tonight interviews cited by Page Six, the medication has really minimized her inflammation. Metz noted that dealing with perimenopause and knee issues made the anti-inflammatory properties of the drug especially beneficial for her stage performances.
Managing Food Noise and Perimenopausal Health Challenges
Beyond physical stamina on stage, Metz highlighted the psychological relief provided by the medication. She told Entertainment Tonight that silencing the constant preoccupation with food has been immensely helpful, allowing her to focus on other aspects of life without obsessing over meals.
E! News reported that Metz initially approached the option as a skeptic before reviewing research provided by a friend. She acknowledged that public opinions on weight-loss drugs remain divided, but she hopes her transparency encourages open conversations for individuals who might benefit from similar medical choices but fear public judgment.
Dietary Shifts and Strength Training Milestones
Metz’s journey to a 100-pound weight loss developed across multiple phases over recent years. In April 2025, she told the Daily Mail that she initially lost weight primarily through strength training and struggled for a long time with vilifying food due to restrictive dieting beliefs.
By August of that same year, she shared an Instagram Story progress report celebrating her physical strength and muscle tone. During that same month, Metz officially confirmed to People that she had begun taking a GLP-1 medication after previously being skeptical of pharmaceutical options for weight management.
Broadway Demands and Physical Endurance
Starring in & Juliet required a level of physical endurance that tested Metz’s joints and energy levels. Performing eight shows a week on a Broadway stage demanded rigorous physical preparation, which she credited the medication and her strength training routine for supporting.
The National Desk noted that Metz has spent the past four months managing the intense performance schedule while navigating perimenopausal symptoms and prior knee issues, making the reduction in physical inflammation a critical factor in her theatrical run.
Frequently Asked Questions About Chrissy Metz and GLP-1 Medications
When did Chrissy Metz start taking a GLP-1 medication?
Metz began her GLP-1 journey in August, following a year in which she lost 100 pounds through a combination of lifestyle changes and strength training.
What specific health benefits has Metz experienced from the drug?
Aside from weight loss, Metz reported that the medication minimized her bodily inflammation, helped her manage perimenopausal and knee issues, and quieted food noise to reduce obsessive thoughts about eating.
How does Metz respond to public opinions regarding weight-loss drugs?
Metz acknowledged that people hold strong opinions about GLP-1 usage, but she views her decision as a personal choice and hopes to destigmatize the conversation so others can explore options that improve their well-being without fear of judgment.
Worth a look