## Global Fund Partners Demonstrate Unity and Resolve to Sustain Progress and Strengthen global Health Security

US$11.34 billion raised amid global challenges marks renewed solidarity and sets the stage for a transformed, more resilient global health system.

21 November 2025

JOHANNESBURG/GENEVA – The Global Fund to Fight AIDS, Tuberculosis and Malaria (the Global Fund) held its Eighth Replenishment Summit today in Johannesburg, South Africa, co-hosted by the governments of the Republic of South Africa and the United Kingdom on the margins of the G20 Leaders’ Summit.Despite one of the most turbulent geopolitical and economic years in recent memory, partners around the world pledged US$11.34 billion to sustain the fight against AIDS, tuberculosis (TB) and malaria, save millions more lives, and strengthen systems for health.

The Summit also marked a renewed commitment to work differently – embracing a more agile, country-driven form of partnership that can adapt to a rapidly changing global health landscape, mobilize new donors, and accelerate domestic resource mobilization for health.

The outcome represents a powerful demonstration of unity and resolve in a period defined by fiscal tightening, conflict and global uncertainty. While total pledges fall short of the aspiring target set in the Investment Case, and several donors have yet to confirm their pledges, this Replenishment nevertheless reaffirms that global solidarity remains strong – and that the world can come together to confront these three epidemics and protect future generations.

Renewed leadership and solidarity

At the Summit, H.E. President Cyril Ramaphosa of South africa underlined africa’s growing leadership in global health.

“Hosting this Replenishment on African soil for the first time symbolizes how far we have come – and how far we can go,” he said. “Africa is not only leading in implementation; we are also driving innovation and taking greater responsibility for our own health systems. This partnership embodies solidarity, equity and transformation.”

five Heads of State and Government, and representatives from more than 30 countries, joined the gathering alongside multilateral partners, philanthropies, businesses, civil society and community networks. Their unity sent a powerful message: The fight against AIDS, TB and malaria is not over – and global resolve to advance progress remains strong.

Rt. Hon. Sir Keir starmer, Prime Minister of the United Kingdom, stressed the value of investing in the Global Fund.

“In today’s volatile world, we must prioritise spending that makes a genuine difference and supports both growth at home and globally,” he said.

“That is why we will continue to support the Global Fund,whose work is at the cutting edge of fighting the world’s deadliest diseases. It is an investment in economic growth and stability, and a prime example of our modern approach to development.”

strong commitments across sectors

Even amid economic headwinds and competing global priorities, partners reaffirmed their confidence in the Global Fund’s impact.

The United Kingdom,as co-host,pledged GBP 850 million for lifesaving prevention,testing and treatment services,emphasizing that this is a strategic investment in global and national health security and in economic growth and stability. South Africa committed US$36.6 million, a joint public-private pledge that includes an increased government contribution, which more than doubled from the last Replenishment, and financing from the south African private sector amounting to US$10 million, exemplifying Africa’s dual role as both implementer and investor.

The United States, the global Fund’s largest don

the Global Fund and Nigeria’s Health System Strengthening

The Global Fund, a worldwide partnership dedicated to accelerating the end of AIDS, tuberculosis, and malaria, continues to play a crucial role in bolstering Nigeria’s health infrastructure. Recent commitments and collaborative efforts signal a renewed focus on strengthening Nigeria’s health systems, expanding access to care, and building resilience against future health challenges.

The Global Fund’s Investment in Nigeria

Nigeria is a key recipient of funding from the Global Fund. These investments are strategically directed towards strengthening primary healthcare,improving disease surveillance,and deploying innovative tools to deliver essential health services,notably to underserved and remote communities.The Global Fund’s support isn’t simply financial; it’s a partnership focused on lasting improvements.

Focus Areas of Investment

• Primary Healthcare Expansion: Funding is allocated to expand the reach and quality of primary healthcare services, forming the foundation of a robust health system. the Global Fund prioritizes strengthening primary care as the most effective way to reach populations with essential health services.
• Disease Surveillance: Strengthening surveillance systems is critical for early detection and rapid response to disease outbreaks. This includes investments in laboratory infrastructure, data collection, and analysis.
• Innovative Tools & Technologies: The Global Fund supports the introduction and scaling up of new tools and technologies, such as rapid diagnostic tests and effective treatment regimens, to improve health outcomes.

Nigeria’s Commitment and Vision

Nigeria’s government is actively aligning the Global Fund’s support with its own national health priorities. This includes a deepening investment in the country’s health system, aiming to build a more resilient and equitable system capable of achieving worldwide health coverage.

As stated by Nigerian officials, this collaboration is about more than just addressing specific diseases; it’s about building a sustainable health system that can serve all citizens, nonetheless of location. “For Nigeria, this aligns with our deepening investment in our own health system – from expanding primary health care to strengthening surveillance and deploying new tools that bring lifesaving services closer to our people. This renewed spirit of solidarity reinforces our determination to build a more resilient, equitable health system and advance universal health coverage, ensuring that every community, no matter how remote, can access quality care.”

Shifting Towards Collaborative Delivery

The Global Fund is actively working to move away from parallel funding streams and towards a more integrated, collaborative approach. This means working with governments, civil society organizations, and the private sector to deliver health services more efficiently and effectively. The global Fund emphasizes the importance of country ownership and alignment with national health strategies.

Looking ahead,the Global Fund is committed to accelerating this collaborative shift – moving from parallel efforts to shared delivery.

Key Takeaways

• The Global Fund is a major partner in strengthening Nigeria’s health system.
• Investments focus on primary healthcare, disease surveillance, and innovative tools.
• Nigeria is committed to aligning Global Fund support with its national health priorities.
• A shift towards collaborative delivery is underway to improve efficiency and impact.

Publication Date: 2025/11/22 17:48:20