2026 NCAA Tournament: West Region Odds, Predictions & Upsets

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2026 NCAA Tournament West Region Preview: Arizona Leads a Competitive Field

The 2026 NCAA Men’s Basketball Tournament West Region is shaping up to be a thrilling battleground, headlined by No. 1 seed Arizona. Coming off a Big 12 Tournament championship, the Wildcats are favored to advance, but face stiff competition from Purdue, Gonzaga, and Arkansas, all of whom have demonstrated the ability to make deep runs in March Madness.

West Region Breakdown: Key Contenders

Arizona enters the tournament with a strong resume and is currently favored to win the West Region. Purdue, the No. 2 seed, also boasts a recent conference tournament victory, having claimed the Big Ten title. Gonzaga, a perennial contender, quietly dominated the West Coast Conference, while Arkansas arrives as the SEC Tournament champion. Wisconsin, also in the mix, rounds out the top teams in this region.

First Round Matchups and Odds

Here’s a look at the opening odds for some key first-round matchups (via FanDuel Sportsbook):

  • No. 16 Long Island University vs. No. 1 Arizona (-31.5)
  • No. 9 Utah State (-2.5) vs. No. 8 Villanova
  • No. 12 High Point vs. No. 5 Wisconsin (-10.5)
  • No. 13 Hawaii vs. No. 4 Arkansas (-15.5)
  • No. 14 Kennesaw State vs. No. 3 Gonzaga (-20.5)
  • No. 15 Queens vs. No. 2 Purdue (-25.5)

Odds to Win the West Region

As of March 17, 2026, the odds to win the West Region are:

  • Arizona: -145
  • Purdue: +450
  • Gonzaga: +1000
  • Arkansas: +900
  • Wisconsin: +1700

National Championship Contenders

The West Region also features several teams with legitimate national championship aspirations. Here are their current odds to win March Madness:

  • Arizona: +330
  • Purdue: +2700
  • Gonzaga: +8000
  • Arkansas: +6000
  • Wisconsin: +12500

Upset Alert: High Point vs. Wisconsin

One potential upset to watch in the first round is High Point against Wisconsin. High Point boasts an elite offense and could challenge Wisconsin in a high-scoring affair. Wisconsin has shown vulnerability, with some surprising losses during the Big Ten season, and is susceptible if their three-point shooting is off. The Panthers excel at forcing turnovers, a potential key to disrupting Wisconsin’s offense.

Looking Ahead

The West Region promises exciting matchups and potential upsets. Arizona is the clear favorite, but Purdue, Gonzaga, and Arkansas are all capable of making a deep run. The region goes through San Jose, California, on the path to the Final Four in Indianapolis. Fans should expect a competitive and unpredictable tournament as these battle-tested teams vie for a spot in the national spotlight.

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