Global Cholera Update: cases and Deaths in 2025
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As of December 28, 2025, a critically important cholera outbreak continues to impact multiple regions worldwide.A cumulative total of 614,828 cholera cases and 7,598 deaths have been reported from 33 countries across five World Health Organization (WHO) regions.
Regional Breakdown
The Eastern Mediterranean Region has been the most heavily affected, reporting the highest number of cases and fatalities. This is followed by the African Region, the South-East Asia Region, the Region of the Americas, and the Western Pacific Region. notably, the European Region has remained unaffected by cholera during this period.
Recent Trends: December 2025
In December 2025 (epidemiological weeks 49 to 52), 17,327 new cases of cholera and acute watery diarrhoea (AWD) were reported across 16 countries within three WHO regions. This represents a 25% decrease in new cases compared to November 2025.
Despite the decrease in cases, 137 cholera-related deaths were reported globally in December, marking a 16% reduction from the previous month. While this indicates a positive trend, the ongoing outbreak continues to pose a serious public health threat.
Ongoing Monitoring and Resources
The WHO is closely monitoring the global cholera situation and providing support to affected countries. Further data and updates can be found at the WHO Cholera Upsurge page.
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