Diphtheria Outbreak in South Africa: Western Cape Emerges as Epicenter
South Africa is currently managing a concerning rise in diphtheria cases, with the Western Cape province identified as the primary center of the increase. Recent data highlights a significant concentration of both confirmed cases and carriers in the region, prompting intensified monitoring and contact tracing efforts by health authorities.
Current State of the Outbreak
The scale of the situation in the Western Cape is substantial. As of January 26, 2026, the majority of confirmed cases and carriers—approximately 76%, or 116 out of 152 individuals—were located in the Western Cape. Among these, 67 cases were specifically identified as toxigenic respiratory diphtheria.
The National Institute for Communicable Diseases (NICD) continues to track the spread of the bacteria. In a situational report for Week 7 of 2026, the NICD confirmed one new laboratory-confirmed case of toxigenic diphtheria, which was detected through active contact tracing efforts.
Understanding Diphtheria
Diphtheria is an infectious disease caused by bacteria. In the pre-vaccination era, the disease was widespread and predominantly affected children under the age of 15. While humans are the primary hosts for the bacteria, modern vaccination efforts have historically kept the disease in check, making recent spikes a point of critical concern for public health officials.
Public Health Response
Authorities in the Western Cape are actively communicating the risks and status of the outbreak to the public. Byron la Hoe, the spokesperson for the Western Cape, has been instrumental in providing updates on the local case counts and the government’s response to the surge in infections.
- Geographic Focus: The Western Cape is the center of the outbreak, accounting for 76% (116/152) of confirmed cases and carriers.
- Case Types: There are 67 confirmed cases of toxigenic respiratory diphtheria in the Western Cape.
- Ongoing Monitoring: The NICD continues to identify new cases through contact tracing, including a laboratory-confirmed toxigenic case in Week 7 of 2026.
- Historical Context: Diphtheria historically targeted children under 15 before the advent of widespread vaccination.
Frequently Asked Questions
What is toxigenic diphtheria?
Toxigenic diphtheria occurs when the bacteria produce a toxin that can cause severe illness, particularly affecting the respiratory system. Recent reports from South Africa have specifically highlighted cases of toxigenic respiratory diphtheria in the Western Cape.

Who is most at risk?
Based on historical data from the pre-vaccination era, children under 15 years ancient were the primary group affected by the disease.
How are new cases being found?
Health authorities are utilizing contact tracing to identify new cases. This method recently led to the detection of a new laboratory-confirmed case of toxigenic diphtheria in early 2026.
Looking Ahead
The concentration of cases in the Western Cape underscores the importance of vigilant surveillance and the maintenance of high vaccination rates. As the NICD continues to release situational reports, the focus remains on containing the spread through rigorous contact tracing and public health interventions to prevent further respiratory diphtheria cases.