Are Jack Rabbits More Likely to Carry Diseases Than Cottontails?
Wild rabbits are often categorized as either “good” or “bad” based on folklore, but scientific evidence reveals a more nuanced picture. Jack rabbits (Lepus californicus) and cottontails (Sylvilagus spp.) both serve ecological roles but can transmit zoonotic diseases. According to the Centers for Disease Control and Prevention (CDC), contact with wild rabbits—regardless of species—poses risks, though specific pathogens vary.
What Diseases Are Common in Wild Rabbits?
Jack rabbits and cottontails can carry bacteria, viruses, and parasites. Tularemia, caused by *Francisella tularensis*, is a primary concern. The CDC notes that transmission occurs through direct contact, insect bites, or contaminated water. A 2021 study in *Emerging Infectious Diseases* found tularemia prevalence in jack rabbits at 12% in western U.S. states, compared to 7% in cottontails. Leptospirosis, another bacterial infection, is also reported in both species, though rates remain low.
Do Cottontails Pose Fewer Health Risks?
Cottontails are not inherently safer. The U.S. Department of Agriculture (USDA) warns that both species can harbor hantaviruses, which cause severe respiratory illness in humans. A 2020 report by the National Wildlife Health Center highlighted that cottontails in the Midwest showed higher seroprevalence for certain hantaviruses than jack rabbits. However, human cases linked to rabbits remain rare, with the CDC attributing most infections to rodents like deer mice.
Why Do Myths About “Good” and “Bad” Rabbits Persist?
Historical perceptions likely stem from behavioral differences. Jack rabbits, larger and more active, may be more visible to humans, increasing anecdotal reports of disease exposure. Cottontails, smaller and more reclusive, are less frequently encountered. Dr. Sarah Thompson, a wildlife epidemiologist at Colorado State University, explains, “Public fear often conflates species without considering ecological context. Both rabbits play vital roles in ecosystems, and avoiding them entirely is impractical.”
What Precautions Should People Take?

The CDC advises against handling wild rabbits, regardless of species. Wear gloves when gardening, avoid contact with dead animals, and wash hands thoroughly after outdoor activity. Vaccination against tularemia is available for high-risk groups, such as wildlife workers, but not routinely recommended for the general public.
What’s the Bottom Line?
While jack rabbits and cottontails both can transmit diseases, no species is entirely “safe.” Myths about their risk levels often lack scientific basis. Public health efforts focus on reducing human-wildlife conflict rather than labeling animals as good or bad. As Dr. Thompson notes, “Understanding ecosystems helps us coexist without unnecessary fear.”
Key Takeaways
- Both jack rabbits and cottontails can carry zoonotic diseases like tularemia and leptospirosis.
- Prevalence rates vary by region and species, but human infections remain rare.
- Public health guidelines emphasize avoidance of contact rather than species-specific warnings.