Second Human Case of H5N1 Avian Influenza Confirmed in Cambodia in 2026
Phnom Penh, Cambodia – Health officials in Cambodia have confirmed a second human case of H5N1 avian influenza (bird flu) in 2026, according to a statement released by the Ministry of Health on Sunday, March 15th. This case follows a previous confirmed infection in February, marking a continued, though limited, spread of the virus to humans.
Details of the New Case
The latest case involves a 45-year-old woman from Banteay Meanchey province, residing in Ropak village, Preah Netr Preah district. The National Institute of Public Health confirmed the H5N1 infection on Saturday, March 14th. Investigations revealed the patient raised both chickens and ducks, and had experienced illness and death among her poultry. She tested positive for the virus three days after direct contact with the deceased birds.
Public Health Response
Cambodian health authorities are actively investigating the source of the infection and are working to identify and monitor any potential additional cases or individuals who may have been in contact with the infected woman. This proactive approach aims to prevent a wider outbreak within the community. Health departments are urged to investigate potential human cases of HPAI A(H5N1) virus infection and notify the CDC within 24 hours of identifying a case under investigation .
Previous Case and Recovery
The first human case of H5N1 avian influenza in Cambodia this year was detected in mid-February in a 30-year-old man from Kampot province. Fortunately, that individual fully recovered from the infection.
Understanding H5N1 Influenza
H5N1 influenza is a virus that primarily affects poultry. While it typically spreads between birds, it can, on occasion, transmit from poultry to humans. Symptoms of H5N1 infection in humans include fever, cough, runny nose, and potentially severe respiratory illness. A recent report details 16 human cases of highly pathogenic avian influenza A (H5N1) virus infection that occurred in Cambodia from February 2023 through August 2024 .
Monitoring and Prevention
Individuals exposed to HPAI A(H5N1) virus-infected birds, dairy cows, or other animals should be monitored for signs and symptoms of acute respiratory illness and conjunctivitis. Monitoring should begin after the first exposure and continue for 10 days after the last exposure .
The Ministry of Health continues to emphasize the importance of vigilance and preventative measures to minimize the risk of further human infections.