Eric Dane, ‘Grey’s Anatomy’ and ‘Euphoria’ Star, Dies at 53 After ALS Battle

Eric Dane, the actor celebrated for his roles in “Grey’s Anatomy” and “Euphoria,” has died at the age of 53 following a battle with amyotrophic lateral sclerosis (ALS), similarly known as Lou Gehrig’s disease. His death was announced on Thursday, February 19, 2026, by his representatives.

ALS Diagnosis and Advocacy

Dane publicly revealed his ALS diagnosis in April 2025 [CBS News]. Throughout his illness, he became a passionate advocate for raising awareness and funding research for the disease [AP News].

Family Statement

A statement released by his family expressed their deep sorrow: “With heavy hearts, we share that Eric Dane passed on Thursday afternoon following a courageous battle with ALS.” The statement continued, noting he spent his final days surrounded by friends, his wife, and his two daughters, Billie and Georgia, who were “the center of his world” [BBC News].

Career Highlights

Dane first gained widespread recognition for his portrayal of Dr. Mark Sloan, affectionately known as “Dr. McSteamy,” on the ABC medical drama “Grey’s Anatomy,” joining the cast in 2006 [BBC News]. He later reprised the role in 2021. Prior to “Grey’s Anatomy,” he appeared in shows like “Charmed” and later took on the role of Cal Jacobs in the HBO teen drama “Euphoria” [BBC News]. His film credits include “X-Men: Last Stand,” “Marley & Me,” “Valentine’s Day,” and “Burlesque” [CBS News].

Personal Life

Eric Dane was married to actress and model Rebecca Gayheart, and together they had two daughters, Billie and Georgia [BBC News].

About ALS

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord, leading to muscle weakness, paralysis, and eventually, death [CBS News]. The cause of ALS is currently unknown, and there is no cure. According to the ALS Association, about 1 in 300 Americans are affected by the disease [CBS News]. Life expectancy following diagnosis is typically three to five years [CBS News].