Eric Dane, ‘Grey’s Anatomy’ and ‘Euphoria’ Star, Dies at 53 After ALS Battle
Eric Dane, best known for his role as Dr. Mark Sloan on the television series “Grey’s Anatomy,” has died at the age of 53 following a battle with amyotrophic lateral sclerosis (ALS), his family announced on Thursday, February 19, 2026. The announcement comes less than a year after Dane publicly revealed his diagnosis in April 2025.
A Courageous Battle and Legacy of Advocacy
“With heavy hearts, we share that Eric Dane passed on Thursday afternoon following a courageous battle with ALS,” his family said in a statement provided to CBS News [1]. He was surrounded by his wife, Rebecca Gayheart, their two daughters, Billie and Georgia, and close friends during his final days. Throughout his struggle with ALS, Dane became a passionate advocate for raising awareness and funding research into the disease.
From ‘Grey’s Anatomy’ to a Prolific Career
Dane rose to prominence playing the role of Dr. Mark Sloan, nicknamed “McSteamy,” on “Grey’s Anatomy” from 2006 to 2012, with a reprise in 2021 [3]. Beyond his iconic role on the medical drama, Dane had a diverse and extensive career in television and film, including appearances in shows like “Euphoria” and “Charmed,” and films such as “X-Men: Last Stand” (2006) and “Burlesque” (2010) [1].
ALS: A Devastating Neurological Disease
ALS, also known as Lou Gehrig’s disease, is a progressive neurodegenerative disease that affects the nervous system, impacting the brain and spinal cord [1]. Approximately 1 in 300 Americans are affected by the disease [1]. The life expectancy following an ALS diagnosis is typically three to five years, according to the Cleveland Clinic [1]. The cause of ALS remains unknown.
Tributes from Colleagues and Fans
Following the announcement of his death, tributes poured in from fellow actors and fans. Ashton Kutcher expressed his condolences on X, noting the loss to their fantasy football league and emphasizing the ongoing fight against ALS [2]. Alyssa Milano remembered Dane’s sharp wit, and Robert Patrick acknowledged his strength and generosity [2].
Eric Dane is survived by his wife, Rebecca Gayheart, and their two daughters.