Hantavirus Outbreak on Cruise Ship MV Hondius: Experts Criticize U.S. Health Response
A rare and serious hantavirus outbreak aboard the cruise ship MV Hondius has sparked international health concerns and a heated debate over the adequacy of the U.S. Government’s response. While health authorities maintain that the risk to the general public remains low, infectious disease experts are calling the lack of transparent communication and immediate action a “travesty.”
- The Outbreak: Three passengers have died and at least eight others have fallen ill on the MV Hondius.
- The Pathogen: The illnesses are caused by the Andes virus, a South American hantavirus capable of person-to-person transmission.
- The Controversy: The Infectious Diseases Society of America (IDSA) has criticized the CDC and NIH for a perceived lack of communication and failure to deploy teams.
- Public Risk: Both the WHO and CDC classify the risk to the general public as low.
Understanding the MV Hondius Outbreak
The outbreak occurred while the MV Hondius was anchored off the coast of Cape Verde, a West African island nation. The ship is currently en route to the Canary Islands. Among the 147 passengers on board, 17 are U.S. Citizens.

The World Health Organization (WHO) first issued an outbreak alert on Monday, providing frequent updates and confirming that scientists in Switzerland and South Africa identified the cause as the Andes virus. In contrast, the Centers for Disease Control and Prevention (CDC) did not publicly acknowledge the situation until late Wednesday, stating that the agency is “closely monitoring the situation” and that the risk to the U.S. Public is “extremely low.”
What is the Andes Virus?
Hantaviruses are typically zoonotic, meaning they spread from animals to humans. According to the CDC, the virus usually spreads through exposure to rodent urine, droppings, or saliva, and occasionally through bites or scratches.
However, the Andes virus is distinct from other strains. While the Sin Nombre virus—responsible for more than 90% of hantavirus cases in the U.S. (mostly west of the Mississippi)—is not known to spread between humans, the Andes virus can be transmitted from person to person, typically through close contact.
The severity of hantavirus is significant; the CDC notes that nearly 40% of people who develop respiratory symptoms related to the disease may die.
Experts Sound the Alarm Over CDC “Silence”
The delay in public communication from U.S. Health officials has drawn sharp criticism from the medical community. During an IDSA press briefing, Jeanne M. Marrazzo, MD, MPH, CEO of the Infectious Diseases Society of America, described the response as a “travesty.”
Carlos del Rio, MD, a professor of global health and epidemiology at Emory University, expressed concern over the absence of standard operating procedures usually seen during such outbreaks. Specifically, Dr. Del Rio highlighted several missing elements in the U.S. Response:
- Lack of Deployment: The CDC typically deploys teams to outbreak sites for epidemiological tracing and interviews.
- No Health Alert Notice (HAN): The agency has not yet issued a formal HAN, which is a standard tool for notifying healthcare providers.
- Communication Gap: There have been no formal briefings from the CDC or NIH.
In response to these concerns, NIH Director Jay Bhattacharya, MD, PhD, who is temporarily leading the CDC, stated that the agency began coordinating with partners as soon as they were notified and provided written health guidance to American passengers via the State Department.
Comparing Hantavirus Strains
| Feature | Andes Virus (Current Outbreak) | Sin Nombre Virus (Common in U.S.) |
|---|---|---|
| Primary Origin | South America | North America (West of Mississippi) |
| Human-to-Human Spread | Yes (via close contact) | No |
| Transmission | Rodents & Human contact | Rodents only |
Looking Ahead
WHO Director-General Tedros Adhanom Ghebreyesus has expressed confidence in Spain’s ability to manage the risk as the ship arrives in the Canary Islands. While the immediate threat to the global population remains low, Dr. Del Rio suggests that this outbreak presents a critical opportunity for scientists to learn more about how the virus transmits between humans.

As the CDC continues to provide technical input and guidance, the IDSA has pledged to fill the current “void” in public health communication to ensure medical professionals and the public remain informed.