Swedish Trial Investigates Pramipexole’s Efficacy in Treating Anhedonia in Depressive Disorders A randomized controlled trial conducted in Lund, Sweden, is evaluating the effectiveness of pramipexole, a dopamine agonist, in reducing …
Molecular Medicine
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Health
Comparing Clinical AI Tools to General-Purpose LLMs: A Quantitative Evaluation of Medical Knowledge, Expert Alignment, and Real-World Clinical Use
Frontier AI Models Outperform Clinical Tools in Medical Benchmarks, Study Finds General-purpose large language models (LLMs) such as Google Gemini and OpenAI GPT-5.2 achieved higher accuracy on medical exams and …
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Microglial Transitions Linked to Dementia Risk and Brain Resilience, New Study Reveals A recent study published in *Nature Medicine* highlights the critical role of microglial transitions in the progression of …
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Understanding Bundibugyo Ebolavirus: Surveillance and Public Health Implications Bundibugyo virus disease (BVD) is a rare but severe viral hemorrhagic fever caused by the Bundibugyo orthoebolavirus, a member of the Filoviridae …
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The Brain Health for Economic Resilience Commission has launched as a global, transdisciplinary initiative to integrate brain health into international economic policy. By establishing standardized metrics for cognitive capacity, the …
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Gene Therapy for Parkinson’s Disease Advances: Latest Trials and Efficacy Data Gene therapy for Parkinson’s disease has seen significant progress, with recent clinical trials demonstrating both promise and challenges. According …
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Health
Dapagliflozin and Heart Failure in Type 2 Diabetes Patients with Rare Cardiomyopathy Variants
Genetic Variants and Dapagliflozin: New Insights into Heart Failure Treatment Patients with type 2 diabetes who carry rare genetic variants associated with cardiomyopathies (CMP) appear to derive similar cardiovascular benefits …
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Health
Ebola Outbreak Exposes Blind Spot in Global Epidemic Preparedness: lessons from the Bundibugyo Virus Crisis
The Ebola outbreak caused by the Bundibugyo virus in the Democratic Republic of the Congo (DRC) and Uganda has been declared a Public Health Emergency of Continental Security by the …
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Clinical Trial Begins for Lassa Fever Vaccine Candidate Researchers at the University of Maryland School of Medicine (UMSOM) have launched a Phase 1 clinical trial to evaluate the safety and …
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Health
Circulating Tumor DNA Monitoring Fails to Prolong Disease-Free Survival in Colorectal Cancer Trial
Circulating Tumor DNA Monitoring in Colorectal Cancer: Findings from the ALTAIR Trial In the phase 3 ALTAIR trial, researchers evaluated whether using trifluridine/tipiracil hydrochloride to treat patients with resected colorectal …