US and Israel Launch Major Assault on Iran Amidst Calls for Regime Change

The United States and Israel launched a major joint military operation against Iran on Saturday, February 28, 2026, escalating regional tensions and prompting a response from Iran targeting both countries. The strikes come after weeks of escalating threats from President Donald Trump, who has vowed to address Iran’s nuclear program and its internal policies.

Operation Epic Fury and Targets

The U.S. Military has dubbed the assault “Operation Epic Fury.” According to reports, the strikes targeted Supreme Leader Ali Khamenei and President Masoud Pezeshkian, as well as other top regime and military commanders. Targets included Iran’s military infrastructure, symbols of government, and intelligence facilities. Several senior Revolutionary Guards commanders and political officials were reportedly killed, including the commander of Iran’s Islamic Revolutionary Guard Corps, Gen. Mohammad Pakpour, and Iranian defense minister Amir Nasirzadeh.

Trump’s Call for Regime Change

President Trump, in a video posted on Truth Social, stated the U.S. Was undertaking the operation to prevent Iran from threatening America and its national security interests. He went further, calling on Iran’s military forces to lay down their weapons and urging Iranian civilians to “seize over your government.” Speaking to the Washington Post, Mr. Trump said his objective was securing freedom and safety for Iran’s people.

Iranian Response and Regional Impact

Iran responded to the strikes with missile launches targeting Israel and at least two major U.S. Military bases in the region. Israel’s military reported multiple rounds of missile attacks. The situation has raised concerns about a broader regional conflict.

Buildup to the Strikes

Prior to the strikes, the U.S. Military had moved over a dozen naval ships and aircraft toward the Middle East as the Trump administration increased pressure on Iran and engaged in indirect nuclear talks with Iranian officials. Trump previously ordered airstrikes on key Iranian nuclear facilities in June 2025.

Congressional Response

House Democrats are scheduled to discuss the strikes on a call tomorrow, February 29, 2026, with many expressing criticism of the decision and calling on the Trump administration to brief Congress.

Key Takeaways

• The U.S. And Israel launched a major joint military operation against Iran on February 28, 2026.
• President Trump has called for the overthrow of the Iranian government.
• Iran has responded with missile attacks targeting Israel and U.S. Bases.
• The situation raises concerns about a potential escalation of conflict in the region.

The situation remains fluid, and further developments are expected as the conflict unfolds. The international community is closely monitoring the situation, and diplomatic efforts to de-escalate tensions are likely to intensify.