It is no secret that as we age, almost everything deteriorates. And our immune system is no exception. One of the effects of this deterioration may be that the immune system is continually activated, with the pilot light on, even when there is no infection. The result is that they are released proinflammatory molecules all the time. The consequence is a paradox: instead of protecting the body, which is its primary function, this permanent inflammatory response can cause tissue damage and contribute to the development of diseases associated with aging (for example, cardiovascular diseases, type 2 diabetes , neurodegenerative diseases and cancer).
It is considered that the inflammaging It is influenced by various factors including oxidative stress, the accumulation of senescent cells (cells that have lost their ability to divide and function correctly) and changes in the microbiota. And of course, as I’m sure some of you may be suspecting, genetics and lifestyle can also influence susceptibility to inflammaging.
When the natural aging process is combined with obesity, chronic inflammation can worsen since, as we know, our friend the adipocyte produces pro-inflammatory molecules. As we age, the immune system may become less efficient at handling inflammation. The presence of obesity can further aggravate this inflammatory response. Another whiting that bites its tail
It is important to clarify that aging itself is not the direct cause of obesity. However, aging is associated with a series of biological, metabolic, social and lifestyle factors that often contribute to the fact that both conditions go hand in hand.
Among these factors we have: