Eric Dane, Grey’s Anatomy Star, Dies at 53 After ALS Battle

Eric Dane, the actor celebrated for his roles in “Grey’s Anatomy” and “Euphoria,” passed away on Thursday, February 19, 2026, at the age of 53, according to a statement released by his representatives. He died less than a year after publicly disclosing his diagnosis of amyotrophic lateral sclerosis (ALS).

ALS Diagnosis and Advocacy

Dane revealed his ALS diagnosis in April 2025 , and subsequently dedicated his time to raising awareness and funding research for the disease. He actively advocated for improved access to care and spoke publicly about the challenges faced by those living with ALS. In June 2025, he addressed health insurance prior authorization concerns at a news conference in Washington, D.C. . His commitment was recognized in September 2025 when he received the ALS Network’s Spokesperson of the Year award .

Career Highlights

Dane rose to prominence in the mid-2000s, captivating audiences as Dr. Mark Sloan, affectionately known as “Dr. McSteamy,” on the ABC medical drama “Grey’s Anatomy.” He appeared in the series from 2006 to 2012, with a reprise in 2021 . His character’s impact was significant enough that Seattle Grace Hospital was later renamed Gray Sloan Memorial Hospital in his honor .

Beyond “Grey’s Anatomy,” Dane showcased his versatility in roles such as Jason Dean on “Charmed,” Captain Tom Chandler on “The Last Ship,” and Cal Jacobs on the HBO series “Euphoria” . He also appeared in films including “X-Men: The Last Stand” (2006), “Marley & Me” (2008), “Valentine’s Day” (2010), “Burlesque” (2010), and “Bad Boys: Ride or Die” (2024) .

Early Life and Personal Background

Born on November 9, 1972, in San Francisco, California , Dane experienced personal tragedy early in life when his father, an architect and Navy veteran, died by suicide when Eric was seven years old . He was raised in his mother’s Jewish faith and had a bar mitzvah . He attended Sequoia High School and San Mateo High School in California, where he played on the varsity water polo team .

Dane was married to actress and model Rebecca Gayheart, and together they had two daughters, Billie and Georgia .

Family Statement

Dane’s family released a statement expressing their grief: “With heavy hearts, we share that Eric Dane passed on Thursday afternoon following a courageous battle with ALS.” They noted that he spent his final days surrounded by friends, his wife, and his daughters, who were “the center of his world.” The statement continued, “He will be deeply missed, and lovingly remembered always. Eric adored his fans and is forever grateful for the outpouring of love and support he’s received.”

This article was updated on February 20, 2026, to reflect the latest information.