‘McSteamy’ No More: ‘Grey’s Anatomy’ and ‘Euphoria’ Star Eric Dane Dies at 53 After ALS Battle

Eric Dane, celebrated for his roles as Dr. Mark “McSteamy” Sloan in Grey’s Anatomy and Cal Jacobs in Euphoria, has died at the age of 53. His death occurred on Thursday, February 19, 2026, less than a year after he publicly revealed his diagnosis of amyotrophic lateral sclerosis (ALS), a form of motor neuron disease.

ALS Diagnosis and Advocacy

Dane first shared his ALS diagnosis in April 2025 , and subsequently dedicated himself to raising awareness for the condition. ALS, also known as Lou Gehrig’s disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord, leading to muscle weakness, paralysis, and eventually, difficulty with essential functions like speaking, eating, and breathing .

A Career Spanning Multiple Hit Series

Dane rose to prominence playing the charismatic Dr. Mark Sloan on Grey’s Anatomy from 2006 to 2012, with a guest appearance in 2021 . He later captivated a new audience with his portrayal of Cal Jacobs, the complex and often unsettling father of Rue Bennett, in the HBO series Euphoria .

Family and Final Days

Dane is survived by his wife, actress Rebecca Gayheart, and their two daughters, Billie and Georgia. According to a statement released by his representatives, he spent his final days surrounded by loved ones . The family has requested privacy during this tricky time.

Additional Roles

Beyond Grey’s Anatomy and Euphoria, Dane’s career included roles in Charmed, The Last Ship, and films such as Marley & Me, Valentine’s Day, and Burlesque .

ALS and Motor Neuron Disease

ALS is the most common form of motor neuron disease, and the terms are often used interchangeably . The disease is terminal and currently has no cure.