Spermidine: The Longevity Molecule & What to Eat for It

by Dr Natalie Singh - Health Editor
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The “Swiss Army Knife” of Longevity: unlocking the Benefits of Spermidine

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Since its revelation in semen, spermidine has been identified in a vast range of organisms, from plants to bacteria. While many might potentially be unfamiliar with the name, Leslie Kenny, founder of Oxford Health SPAN, calls spermidine the “Swiss army knife of long life,” highlighting its remarkable benefits.

The advantages of spermidine, extending from hair growth to heart health, are numerous.

Studies indicate that this naturally occurring compound can enhance brain health,bolster immunity,strengthen the cardiovascular system,and improve overall appearance.

Found in foods like breast milk, wheat seeds, soybeans, aged cheese, mushrooms, and peas, spermidine plays a crucial role in slowing aging, protecting against disease, combating inflammation, and supporting metabolism.Research suggests spermidine can rejuvenate the immune system, potentially protecting against cancer, pathogens, and autoimmune attacks. Chronic inflammation, linked to conditions like diabetes, heart disease, and muscle pain, can be reduced through spermidine supplementation.Furthermore, it may even help clear toxic proteins like amyloid-beta and TAU, associated with Alzheimer’s disease.It provides hormonal balance

In a study conducted in 2023, spermidine was called “groundbreaking” in terms of hormonal health and fertility, because the research showed that spermidine increases egg quality in old mice.

The same study showed that spermidine can definitely help hormone balancing and urinary incontinence.

Spermidine supplement users experienced a notable decrease in cortisol levels,the stress hormone,in almost all test subjects,and a 50% increase in testosterone levels in male subjects.

Spermidine: A Potential Ally in Cancer Treatment, But Proceed with Caution

Spermidine, a naturally occurring polyamine found in various foods and within our cells, is gaining attention for its potential health benefits, including a possible role in cancer management. Research suggests a complex relationship between spermidine and cancer, where its effects can vary depending on the stage of the disease.

The key lies in autophagy, a cellular “self-cleaning” process that spermidine can stimulate. in healthy cells, autophagy removes damaged components, promoting cellular health and longevity. Though, the balance is critically important in cancer. Spermidine can help to extract cancerous cells at an early stage, and in advanced tumors can sometimes use this system “in favor,” stating Montenegro.

Thus, the use of spermidine in cancer treatment should be approached with caution and always under the supervision of a physician. The cancer history of each individual should be carefully considered before incorporating spermidine into a treatment plan.The lowest effective dose of spermidine is one milligram a day, Kenny said that it is challenging to reach this level with onyl diet, it is difficult to get this amount from food sources, but the reinforcement is more cultivated and continued:“Still, I want people to turn to plants if they can, because the fiber is really valuable,” he said.

supports hair growth and prevents hair whitening

The same fast cell regeneration provides direct benefit to hair,skin and nails.The natural colour of our hair comes from melan.

The Potential of spermidine: Boosting Brain Function and Combating Age-Related Decline

In a 2020 study, spermidine supplementation was found to protect against cognitive decline, memory loss, and motor impairments associated with aging. This suggests a promising avenue for supporting brain health and potentially mitigating the effects of age-related neurological changes.

the research highlights spermidine’s potential role in maintaining optimal brain function as we age, offering hope for a future where cognitive vitality remains strong for longer.

“Bu, bir başlangıç değil, bir son.”

Kaynak: New York post

Spermidine: A Promising Supplement for Longevity and Health

Liver fat that is not connected to alcohol

(NAFLD) happens when too much fat builds up in the liver of people who drink little to no alcohol. It’s usually caused by obesity and metabolic risk factors like type 2 diabetes, high blood pressure, high cholesterol, and sleep apnea.

“In pre-clinical and animal experiments, spermidine reverses these effects,” said Kenny, adding that he’s developed a metabolic function and it truly seems to lower LDL, or bad cholesterol.

Source: New York Post

Spermidine is a naturally occurring compound found in foods, and it’s gaining attention for its potential health benefits. Research suggests it could play a role in slowing aging and improving overall health. But what should you consider before taking a spermidine supplement?

potential Benefits of Spermidine

  • Autophagy: Spermidine is known to promote autophagy, a process where cells clean out damaged components. This cellular “housekeeping” is crucial for maintaining healthy tissues and organs.
  • Heart Health: Studies indicate spermidine may help lower blood pressure and improve cardiovascular function.
  • Brain Health: Some research suggests spermidine could protect against cognitive decline and improve memory.
  • Longevity: By supporting cellular health, spermidine may contribute to a longer lifespan.
  • Liver Health: As noted in recent studies, spermidine may help reverse the effects of non-alcoholic fatty liver disease (NAFLD) and lower bad cholesterol.

What to consider Before Taking Spermidine

While spermidine shows promise, it’s critically important to be informed before adding it to your routine.

  • Age: The potential benefits of spermidine may increase as you get older.
  • Cancer History: If you have a history of cancer or are currently undergoing treatment, always consult with your oncologist before taking spermidine.
  • Medical Supervision: It’s essential to have your doctor monitor you while taking spermidine to ensure it’s safe and effective for your individual needs.

Spermidine is found in foods like wheat germ, soybeans, mushrooms, aged cheese, and certain fruits. however, the amounts in these foods may not be sufficient to achieve the levels used in research studies.Supplements are available, but it’s crucial to choose a reputable brand and discuss dosage with your healthcare provider.

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