Common vaccine myths, including debunked claims about autism and COVID-19 vaccine safety, continue to circulate among the U.S. public, contributing to a "malleable middle" of uncertainty that influences childhood vaccination rates. According to the KFF Tracking Poll on Health Information and Trust, adults who lack a trusted health care provider or rely heavily on social media for medical advice are significantly more likely to endorse these falsehoods.
Why Are Vaccine Myths Still Pervasive?
Despite extensive scientific consensus on the safety and efficacy of vaccines, many Americans remain exposed to misinformation. Two-thirds of adults report having heard the false claim that the measles, mumps, and rubella (MMR) vaccine causes autism, a myth stemming from a study that was officially retracted by The Lancet in 2010.

Other persistent myths include the belief that more people have died from COVID-19 vaccines than from the virus itself (46% have heard this) and that mRNA vaccines can alter human DNA (36% have heard this). While exposure to these claims is high, only a small minority of adults are "consistent myth believers." Most people fall into a state of uncertainty or "malleable" belief, where they are unsure of the validity of these claims.
How Does a Trusted Provider Impact Belief?
The relationship between a patient and their physician is a primary factor in filtering health misinformation. Data from KFF indicates that adults with a trusted health care provider are half as likely to believe that COVID-19 vaccines have caused more deaths than the virus compared to those who lack such a relationship (24% versus 46%).
This correlation persists even when researchers control for variables like education, race, and partisanship. For many, the lack of a trusted provider may stem from systemic barriers, such as being uninsured, or a broader decline in trust toward the medical establishment.
The Role of Social Media and AI in Health Information
Frequent use of social media and artificial intelligence (AI) chatbots for health advice is strongly linked to the endorsement of vaccine myths. Adults who consult social media for health information at least weekly are more than twice as likely to believe the MMR-autism link compared to those who do not use social media for health advice (37% versus 16%).
While AI tools are increasingly used for medical inquiries, regular users of these platforms also show higher rates of believing misinformation regarding mRNA technology and measles vaccines. This suggests that algorithmic content delivery may prioritize engaging, albeit inaccurate, health narratives over verified medical evidence.
How Misinformation Affects Childhood Vaccination
The impact of these myths is most visible in parental decision-making. Parents who report skipping or delaying recommended childhood vaccines are significantly more likely to endorse false claims. Specifically:
- MMR-Autism link: 57% of parents who delay vaccines believe this is true, compared to 30% of parents who keep children up-to-date.
- COVID-19 vaccine safety: 55% of parents who delay vaccines believe more people died from the vaccine than the virus, compared to 29% of those who follow recommended schedules.
Nearly half of parents who delay or skip vaccines fall into the "mixed middle" category of belief, suggesting that their decisions are driven by confusion rather than firm anti-vaccine ideology.
Addressing the "Mixed Middle"
Public health efforts to improve vaccination rates may find the most success by targeting the "mixed middle"—the 31% of the population that holds a mix of true and false beliefs and expresses uncertainty. This group is disproportionately composed of younger adults, Hispanic and Black adults, and those without a college degree. Providing clear, accessible, and empathetic communication through trusted local providers remains the most effective strategy for dispelling the confusion that fuels vaccine hesitancy.

Frequently Asked Questions
Does the MMR vaccine cause autism?
No. Extensive research, including large-scale epidemiological studies, has consistently shown no link between the MMR vaccine and autism. The original study that suggested this link was discredited and retracted.
Can mRNA vaccines change human DNA?
No. According to the Centers for Disease Control and Prevention (CDC), mRNA vaccines do not interact with or alter a person’s DNA. The mRNA delivers instructions to cells to produce a protein that triggers an immune response and is then broken down by the body.
Why do some people fall into the "mixed middle"?
The "mixed middle" consists of individuals who are exposed to conflicting information and lack a primary, trusted source to help them interpret it. This uncertainty often leads to hesitation regarding medical decisions.