Eric Dane, ‘Grey’s Anatomy’ and ‘Euphoria’ Star, Dies at 53 After ALS Diagnosis
Eric Dane, known for his roles as Dr. Mark Sloan in “Grey’s Anatomy” and Cal Jacobs in “Euphoria,” has died at the age of 53, following a battle with amyotrophic lateral sclerosis (ALS). His representatives confirmed his death to multiple American media outlets on February 19, 2026.
ALS Diagnosis and Public Disclosure
Dane publicly revealed his diagnosis of ALS, likewise known as Charcot disease, in April 2025. People Magazine exclusively reported the news, with Dane expressing gratitude for his family’s support as he navigated the illness.
Career Highlights
Dane first gained widespread recognition for his portrayal of Dr. Mark Sloan, nicknamed “McSteamy,” on “Grey’s Anatomy” from 2006 to 2012, with a brief return in season 17. More recently, he captivated a new audience with his complex and compelling performance as Cal Jacobs in HBO’s “Euphoria.”
His career spanned over three decades, including roles in television series from the 1990s and 2000s, and films such as “X-Men: The Last Stand.” The BBC noted his diverse body of work.
Advocacy and Commitment to ALS Research
After going public with his diagnosis, Dane dedicated himself to raising awareness and supporting research efforts for ALS. He expressed a desire to use his platform to help others facing the disease, and actively engaged with organizations focused on funding and legislative issues related to ALS. YouTube reported on his commitment to raising awareness.
ALS: Understanding the Disease
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord, leading to muscle weakness, paralysis, and eventually, death. According to the BBC, it is the most common form of motor neurone disease (MND).
Family Statement
Dane’s family released a statement through People, expressing their grief and acknowledging his “courageous fight” against the illness, surrounded by his loved ones, wife Rebecca Gayheart, and their two daughters.