Historic Dual Heart and Liver Transplant Saves Young Girl at Children’s Hospital Colorado
In a rare and life-saving procedure, Children’s Hospital Colorado successfully completed its first pediatric dual heart and liver transplant, offering a second chance at life for 11-year-old Gracie Greenlaw. The complex, 16-hour surgery marks a significant milestone for the hospital and the Rocky Mountain region.
A Complex Condition and the Need for Transplant
Gracie was born with hypoplastic left heart syndrome (HLHS), a congenital heart defect where the left side of the heart is underdeveloped [Children’s Hospital Colorado]. She underwent three major surgeries – the Norwood, the Glenn, and the Fontan – before the age of three to help her circulation function [KRDO]. While these surgeries allowed her to live, they could lead to long-term complications, including liver dysfunction and eventual liver failure.
From Fontan Clinic to Transplant Decision
To address these potential long-term effects, Children’s Hospital Colorado established the Fontan Multidisciplinary Clinic in 2016, specializing in the care of patients with HLHS and similar conditions [Children’s Hospital Colorado]. Gracie received integrated care from cardiologists and hepatologists who closely monitored her condition. Over time, she also developed plastic bronchitis, a condition causing protein deposits in her airways, further exacerbating her liver issues. Her medical team determined a dual transplant offered the best long-term outlook.
The Historic Surgery
In April 2025, Gracie was placed on the waiting list for both a heart and a liver [KRDO]. Less than a month later, compatible donor organs became available. Due to the limited viability of donor hearts, the heart transplant was performed first by Dr. Matthew Stone and Dr. Emily Downs, lasting nine hours [Medicine.net]. The donor liver was preserved using a TransMedics Organ Care System, which mimics the body’s normal function, extending its viability. Dr. Megan Adams and Dr. Kendra Conzen then performed the seven-hour liver transplant [Medicine.net]. The surgery involved dozens of specialists across 25 different multidisciplinary teams [Children’s Hospital Colorado].
Recovery and Future Outlook
The transplant was a success, and Gracie was discharged from the hospital just over a month later [KRDO]. Seven months post-transplant, she has returned to school and is enjoying time with her dogs. While she will likely require another heart transplant in the future, her transplanted liver is expected to function for the rest of her life.
“This procedure showcases the expertise, talent, and level of care Children’s Colorado provides to our patients, including those with complex medical needs,” said Dr. Duncan Wilcox, Surgeon in Chief [Children’s Hospital Colorado]. Fewer than 40 such surgeries have been completed in the United States [KRDO].