MV Hondius Hantavirus Outbreak: What You Need to Know About the Rare Andes Virus
What began as a luxury expedition across the Atlantic has turned into a global health concern. Passengers and crew aboard the cruise ship MV Hondius are facing strict isolations and repatriation efforts following an outbreak of the Andes virus, a rare and potent strain of hantavirus. Unlike most hantaviruses, which are contracted through rodent exposure, the Andes strain is uniquely dangerous due to its ability to spread between humans.
This outbreak has triggered a complex international response involving the World Health Organization (WHO), multiple national health ministries, and specialized quarantine facilities. For those tracking the situation or concerned about hantavirus risks, understanding the nature of this virus and the current status of the MV Hondius is critical.
Timeline of the Outbreak
The MV Hondius departed from Ushuaia, Argentina, on April 1, 2026. The health crisis unfolded over several weeks as the ship navigated toward the Atlantic:

- Initial Casualty: The first passenger death occurred on April 11.
- International Spread: A passenger’s body was brought ashore in Saint Helena on April 24; shortly after, their spouse died in a hospital in Johannesburg.
- Onboard Escalation: A third passenger died on the ship, and another British national was transported to Johannesburg in critical condition.
- Evacuation: After receiving approval from the Spanish Ministry of Health, the ship docked at the port of Granadilla in Tenerife, Canary Islands, on May 10.
Understanding the Andes Virus and HPS
To understand why this outbreak is so concerning, it is necessary to distinguish between general hantaviruses and the Andes strain. Most hantaviruses cause either Hantavirus Pulmonary Syndrome (HPS) in the Americas or Hemorrhagic Fever with Renal Syndrome (HFRS) in Europe and Asia. These are typically zoonotic, meaning they jump from animals—specifically rodents—to humans via urine, droppings, or saliva.
The Andes virus is the outlier. It is the only known hantavirus capable of person-to-person transmission. While this usually requires close, sustained contact, the potential for human-to-human spread transforms a localized zoonotic event into a potential public health emergency, necessitating the strict quarantine measures seen with the MV Hondius passengers.
HPS is a severe respiratory disease. Early symptoms often mimic the flu—including fatigue, fever, and muscle aches—but can rapidly progress to coughing and shortness of breath as the lungs fill with fluid, leading to respiratory failure.
The Repatriation and Quarantine Process
The evacuation of the MV Hondius has been a massive logistical undertaking. As of May 12, 122 individuals—comprising 87 passengers and 35 crew members—have been evacuated and sent back to their home countries.
Because of the risks associated with the Andes virus, repatriation does not mean an immediate return to normal life. Many American passengers have been transported to the National Quarantine Unit in Omaha, Nebraska. In these facilities, individuals are kept in isolation to ensure they do not harbor the virus before being cleared for release.
The remaining crew and medical staff are currently sailing the MV Hondius to Rotterdam, Netherlands, where the vessel will undergo a comprehensive professional disinfection process.
Key Takeaways: MV Hondius Outbreak
- The Pathogen: The outbreak was caused by the Andes virus, a rare strain of hantavirus.
- The Danger: Unlike other hantaviruses, the Andes strain can spread from person to person.
- The Toll: Three deaths have been confirmed in connection with the outbreak.
- The Response: Passengers were evacuated via Tenerife and are undergoing strict quarantine in their respective home countries.
- Current Status: The ship is headed to Rotterdam for deep cleaning and disinfection.
Frequently Asked Questions
How is hantavirus usually spread?
In most cases, humans are infected through contact with the urine, droppings, or saliva of infected rodents. This often happens when dried droppings are stirred up into the air and inhaled. Bites or scratches from rodents can also transmit the virus, though this is rare.

Can the general public catch the Andes virus?
The risk to the general public remains extremely low. Person-to-person transmission of the Andes virus is rare and typically occurs only among people with exceptionally close contact with an infected individual. There is no evidence of widespread community transmission outside of the affected group.
What are the early warning signs of HPS?
Early symptoms typically appear one to eight weeks after exposure and include fever, fatigue, and muscle aches—particularly in the thighs, hips, and back. Some patients also experience nausea, vomiting, or dizziness before the onset of severe respiratory distress.
For more information on hantavirus prevention and symptoms, visit the Centers for Disease Control and Prevention (CDC).